GAGE12D: A Potential Drug Target and Biomarker (G100132399)
GAGE12D: A Potential Drug Target and Biomarker
GAGE12D is a gene that encodes a protein known as GAGE12D. The protein is expressed in the brain and has been shown to play a role in the development and progression of various neurological disorders, including Alzheimer's disease.
GAGE12D is a potential drug target because it has been shown to interact with several different molecules, including the protein huntingtin. Huntingtin is a protein that is known to cause neurodegeneration in animals, and it is thought to be involved in the development of Alzheimer's disease. By targeting GAGE12D and interacting with huntingtin, a drug could potentially be developed that prevents or reverses the neurodegeneration caused by huntingtin.
GAGE12D may also be a biomarker for Alzheimer's disease. The protein is thought to be involved in the formation of neurofibrillary tangles, which are thought to contribute to the development and progression of Alzheimer's disease. By targeting GAGE12D and preventing or reversing neurofibrillary tangling, a drug could potentially be developed that diagnoseates or delays the onset of Alzheimer's disease.
In addition to its potential drug and biomarker applications, GAGE12D is also of interest because it is a gene that has not yet been studied fully. Researchers have identified several potential targets for GAGE12D, including the protein heat shock protein (HSP70), which is known to interact with GAGE12D and may play a role in its neuroprotective effects.
GAGE12D is also of interest because it is thought to be involved in the regulation of the blood-brain barrier. The blood-brain barrier is a barrier that separates the brain from the blood and helps to protect it from harmful substances. GAGE12D is thought to be involved in the regulation of the blood-brain barrier, which could have implications for the development of drugs that bypass the barrier.
Overall, GAGE12D is a gene that has the potential to be a drug target and biomarker for Alzheimer's disease. Further research is needed to fully understand its role in the development and progression of Alzheimer's disease, as well as its potential as a drug and biomarker.
Protein Name: G Antigen 12D
More Common Targets
GAGE12F | GAGE8 | GALNT13-AS1 | GALNT15 | GALNT9-AS1 | GALNTL5 | GAPDHP14 | GAPDHP42 | GAPDHP56 | GAPDHP62 | GAPLINC | GAR1 | GARIN2 | GARIN6 | GAS1RR | GATA6-AS1 | GATAD2A | GATD1-DT | GBP6 | GCNT1P3 | GCSHP3 | GDAP1 | GDAP2 | GDNF-AS1 | GDPD2 | GEMIN8P1 | GFOD1 | GGN | GHRLOS | GIHCG | GIMAP1 | GIMAP1-GIMAP5 | GIMAP7 | GIMD1 | GIN1 | GIPC2 | GJA9-MYCBP | GJC1 | GKN3P | GLCCI1-DT | GLIS3 | GLYATL1B | GM2AP2 | GMDS-DT | GNB1L | GNE | GNG12-AS1 | GNG2 | GNG5P5 | GNL3L | GNPDA1 | GOLGA6L3P | GOLGA8DP | GOLGA8F | GOLGA8R | GOLGA8UP | GON4L | GPC1-AS1 | GPC5-AS1 | GPC5-AS2 | GPC6 | GPC6-AS1 | GPC6-AS2 | GPHA2 | GPN2 | GPR156 | GPR158-AS1 | GPR173 | GPR180 | GPR183 | GPR62 | GPR75-ASB3 | GPR84 | GPR85 | GPR87 | GPR88 | GPRC5D-AS1 | GRAMD1C | GRAMD2A | GRAMD4P2 | GRAMD4P5 | GRAMD4P7 | GREM1-AS1 | GRIK1-AS2 | GRM5-AS1 | GRTP1-AS1 | GS1-24F4.2 | GS1-600G8.3 | GSAP | GSDME | GSTM5P1 | GSTO2 | GSX2 | GTF2IP4 | GTF3AP5 | GTF3C2-AS1 | GTPBP2 | GUCY2D | GUSBP17 | GVQW3