Target Name: AP1S1
NCBI ID: G1174
Review Report on AP1S1 Target / Biomarker Content of Review Report on AP1S1 Target / Biomarker
AP1S1
Other Name(s): adapter-related protein complex 1 sigma-1A subunit | golgi adaptor HA1/AP1 adaptin sigma-1A subunit | Adapter-related protein complex 1 sigma-1A subunit | AP19 | FLJ92436 | adaptor-related protein complex 1 subunit sigma-1A | SIGMA1A | Sigma1A subunit of AP-1 clathrin adaptor complex | Adaptor-related protein complex 1 subunit sigma-1A | Sigma1A-adaptin | Golgi adaptor HA1/AP1 adaptin sigma-1A subunit | clathrin-associated/assembly/adaptor protein, small 1 (19kD) | Clathrin-associated/assembly/adaptor protein, small 1 (19kD) | Sigma 1a subunit of AP-1 clathrin | clathrin coat assembly protein AP19 | sigma1A subunit of AP-1 clathrin adaptor complex | CLAPS1 | Adaptor protein complex AP-1 sigma-1A subunit | AP1S1_HUMAN | Adaptor related protein complex 1 subunit sigma 1 | adaptor protein complex AP-1 subunit sigma-1A | sigma1A-adaptin | adaptor related protein complex 1 subunit sigma 1 | EKV3 | HA1 19 kDa subunit | WUGSC:H_DJ0747G18.2 | AP-1 complex subunit sigma-1A | clathrin assembly protein complex 1 sigma-1A small chain | Clathrin coat assembly protein AP19 | MEDNIK | Adaptor protein complex AP-1 subunit sigma-1A | adaptor related protein complex 1 sigma 1 subunit | Clathrin assembly protein complex 1 sigma-1A small chain | Sigma-adaptin 1A

AP1S1: A Drug Target / Disease Biomarker

AP1S1 is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 17 and encodes a protein known as AP-1S1, which is a transcription factor that plays a role in the regulation of cell growth and differentiation.

One of the key features of AP-1S1 is its ability to induce apoptosis, which is the process by which cells naturally die when they are no longer needed or when they have reached their maximum lifespan. This process is important for the development and progression of many diseases, including cancer. By promoting apoptosis, AP-1S1 can help to eliminate cells that have become damaged or dysfunctional, which can lead to the formation of tumors or other cancerous growths.

In addition to its role in cell death, AP-1S1 has also been shown to play a key role in the regulation of cell proliferation. By controlling the activity of other genes, AP-1S1 can promote the growth and development of cells, which is important for the growth and maintenance of tissues and organs.

The potential drug target for AP-1S1 is due to its involvement in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In cancer, AP-1S1 has been shown to promote the growth and survival of cancer cells, making it an attractive target for researchers to explore as a potential drug.

One of the challenges in studying AP-1S1 as a drug target is its complex biology. The gene is involved in a wide range of cellular processes, and it is not clear how all of these processes are connected. Additionally, the structure and function of AP-1S1 are not well understood, which can make it difficult to design small molecules that specifically interact with the protein.

Despite these challenges, research into AP-1S1 is ongoing, and there is a growing interest in using it as a drug target or biomarker. Some researchers are using techniques such as RNA interference and gene editing to try to disrupt the activity of AP-1S1 and understand its role in disease. Others are using techniques such as mass spectrometry and biochemical assays to try to understand its structure and function.

If AP-1S1 is found to be a valid drug target or biomarker, it has the potential to revolutionize the treatment of a wide range of diseases. For example, by inhibiting the activity of AP-1S1, researchers may be able to develop new treatments for cancer, neurodegenerative diseases, and autoimmune disorders. Additionally, by understanding the mechanisms behind its activity, researchers may be able to identify new targets for drugs that are currently used to treat these diseases.

In conclusion, AP-1S1 is a gene that has the potential to be a drug target or biomarker for the treatment of various diseases. Its complex biology and lack of understanding make it an attractive target for researchers to explore, and if its potential is confirmed, it has the potential to revolutionize the treatment of a wide range of diseases. Further research is needed to fully understand its role and potential as a drug target or biomarker.

Protein Name: Adaptor Related Protein Complex 1 Subunit Sigma 1

Functions: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules

The "AP1S1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AP1S1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.tech.

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AP1S2 | AP1S3 | AP2A1 | AP2A2 | AP2B1 | AP2M1 | AP2S1 | AP3B1 | AP3B2 | AP3D1 | AP3M1 | AP3M2 | AP3S1 | AP3S2 | AP4B1 | AP4B1-AS1 | AP4E1 | AP4M1 | AP4S1 | AP5B1 | AP5M1 | AP5S1 | AP5Z1 | APAF1 | APBA1 | APBA2 | APBA3 | APBB1 | APBB1IP | APBB2 | APBB3 | APC | APC2 | APCDD1 | APCDD1L | APCDD1L-DT | APCS | APEH | APELA | APEX1 | APEX2 | APH1A | APH1B | API5 | APIP | APLF | APLN | APLNR | APLP1 | APLP2 | APMAP | APOA1 | APOA1-AS | APOA2 | APOA4 | APOA5 | APOB | APOBEC1 | APOBEC2 | APOBEC3A | APOBEC3A_B | APOBEC3B | APOBEC3B-AS1 | APOBEC3C | APOBEC3D | APOBEC3F | APOBEC3G | APOBEC3H | APOBEC4 | APOBR | APOC1 | APOC1P1 | APOC2 | APOC3 | APOC4 | APOC4-APOC2 | APOD | APOE | APOF | APOH | APOL1 | APOL2 | APOL3 | APOL4 | APOL5 | APOL6 | APOLD1 | Apolipoprotein B mRNA editing complex | APOM | APOO | APOOL | APOOP2 | APOOP5 | APP | APPAT | APPBP2 | APPL1 | APPL2 | APRG1 | APRT