IGHVIII-82: The Potential Drug Target and Biomarker (G28338)

Target Name: IGHVIII-82

NCBI ID: G28338

IGHVIII-82

Other Name(s): IGHVIII82 | immunoglobulin heavy variable (III)-82 (pseudogene) | Immunoglobulin heavy variable (III)-82 (pseudogene) | 3-82P

IGHVIII-82: The Potential Drug Target and Biomarker

The immune system is a critical element of human health, as it protects the body against various diseases and pathogens. One of the key proteins involved in the immune response is the interleukin-high value variable (IGHVIII), which is a key signaling molecule in T-cells. IGHVIII plays a crucial role in regulating the immune response and is often elevated in diseases such as cancer, autoimmune disorders, and infections.

The IGHVIII gene has eight exons, which result in a protein that has a molecular weight of approximately 180 kDa. This protein is composed of a variable region that includes a nucleotide sequence of 82 amino acids. The IGHVIII protein is expressed in various tissues and cells of the body, including spleen, thymus, spleen-derived immune cells, peripheral blood T cells, and natural killer cells.

IGHVIII-82 as a Drug Target

The IGHVIII protein has been identified as a potential drug target due to its various functions in the immune system. One of the key functions of IGHVIII is its role in regulating T-cell proliferation and differentiation. IGHVIII has been shown to promote the survival and proliferation of T-cells, which are critical for the immune response.

In addition to its role in T-cell biology, IGHVIII has also been shown to play a key role in the regulation of inflammation. IGHVIII has been shown to regulate the production of pro-inflammatory cytokines, such as interleukin-1 (IL-1), and to protect against the production of anti-inflammatory cytokines, such as transforming growth factor-beta (TGF-beta).

IGHVIII-82 as a Biomarker

IGHVIII-82 has also been identified as a potential biomarker for various diseases. For example, IGHVIII-82 has been shown to be elevated in various types of cancer, including breast, ovarian, and prostate cancer. In addition, IGHVIII-82 has also been shown to be elevated in autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

IGHVIII-82 has also been shown to be elevated in diseases that result from an imbalance in the immune system, such as allergies and infections. In addition, IGHVIII-82 has been shown to be associated with various diseases, such as obesity and diabetes.

Conclusion

In conclusion, IGHVIII-82 is a protein that has important roles in the immune system and has been identified as a potential drug target and biomarker. Further research is needed to fully understand the functions of IGHVIII-82 and its potential as a drug.

Protein Name: Immunoglobulin Heavy Variable (III)-82 (pseudogene)

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•   general information;
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•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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