AAAS
Review Report on AAAS Target / Biomarker Content of Review Report on AAAS Target / Biomarker
AAAS

Related Diseases

1) Triple A Syndrome
Achalasia-Addisonianism-Alacrima Syndrome, also known as allgrove syndrome, is related to congenital nervous system abnormality and familial glucocorticoid deficiency, and has symptoms including ataxia and muscle weakness. An important gene associated with Achalasia-Addisonianism-Alacrima Syndrome is AAAS (Aladin WD Repeat Nucleoporin), and among its related pathways/superpathways are Gene expression (Transcription) and Metabolism of proteins. The drugs Tetracosactide and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, eye and skin, and related phenotypes are achalasia and generalized hyperpigmentation

2) Endometriosis
Endometriosis, also known as endometriosis, site unspecified, is related to endometriosis of ovary and endometrial adenocarcinoma, and has symptoms including pelvic pain and pain and other symptoms associated with female genital organs. An important gene associated with Endometriosis is ENDO1 (Endometriosis, Susceptibility To, 1), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Dienogest and Progesterone have been mentioned in the context of this disorder. Affiliated tissues include uterus, ovary and skin.

3) Familial Glucocorticoid Deficiency
Familial Glucocorticoid Deficiency, also known as glucocorticoid deficiency, is related to glucocorticoid deficiency 1 and achalasia-addisonianism-alacrima syndrome. An important gene associated with Familial Glucocorticoid Deficiency is MC2R (Melanocortin 2 Receptor), and among its related pathways/superpathways are GPCR downstream signalling and Diseases of glycosylation. The drugs Dexamethasone acetate and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, adrenal cortex and cortex, and related phenotypes are decreased circulating cortisol level and failure to thrive

4) Addison Disease
Hypoadrenocorticism, Familial, also known as addison disease, is related to intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies and autoimmune polyendocrine syndrome, type ii. An important gene associated with Hypoadrenocorticism, Familial is ABCD1 (ATP Binding Cassette Subfamily D Member 1), and among its related pathways/superpathways are Metabolism and Diseases of glycosylation. The drugs Tetracosactide and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, adrenal cortex and cortex, and related phenotypes are decreased circulating cortisol level and failure to thrive

The "AAAS Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AAAS comprehensively including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

11beta-Hydroxysteroid Dehydrogenase | 14-3-3 Protein | 15-Lipoxygenase | 17-beta-Hydroxysteroid dehydrogenase | 28S ribosomal subunit, mitochondrial | 3-Ketoacyl-CoA Thiolase (3-KAT) | 39S ribosomal subunit, mitochondrial | 4EHP-GYF2 complex | 5-Hydroxytryptamine Receptor | 5-Hydroxytryptamine Receptor 1 (5-HT1) | 5-Hydroxytryptamine Receptor 2 (5-HT2) | 60S Ribosome | 9-1-1 cell-cycle checkpoint response complex | A-Kinase Anchor Proteins | A1BG | A1BG-AS1 | A1CF | A2M | A2M-AS1 | A2ML1 | A2MP1 | A3GALT2 | A4GALT | A4GNT | AAAS | AACS | AACSP1 | AADAC | AADACL2 | AADACL2-AS1 | AADACL3 | AADACL4 | AADACP1 | AADAT | AAGAB | AAK1 | AAMDC | AAMP | AANAT | AAR2 | AARD | AARS1 | AARS2 | AARSD1 | AASDH | AASDHPPT | AASS | AATBC | AATF | AATK | ABALON | ABAT | ABCA1 | ABCA10 | ABCA11P | ABCA12 | ABCA13 | ABCA17P | ABCA2 | ABCA3 | ABCA4 | ABCA5 | ABCA6 | ABCA7 | ABCA8 | ABCA9 | ABCB1 | ABCB10 | ABCB11 | ABCB4 | ABCB5 | ABCB6 | ABCB7 | ABCB8 | ABCB9 | ABCC1 | ABCC10 | ABCC11 | ABCC12 | ABCC13 | ABCC2 | ABCC3 | ABCC4 | ABCC5 | ABCC6 | ABCC6P1 | ABCC6P2 | ABCC8 | ABCC9 | ABCD1 | ABCD2 | ABCD3 | ABCD4 | ABCE1 | ABCF1 | ABCF1-DT | ABCF2 | ABCF3 | ABCG1 | ABCG2

Disease Target / Biomarker