AASS Related Diseases

AASS

Related Diseases

1) Metabolic Diseases
3-Hydroxyacyl-Coa Dehydrogenase Deficiency, also known as hadh deficiency, is related to long-chain 3-hydroxyacyl-coa dehydrogenase deficiency and hyperinsulinemic hypoglycemia, familial, 4, and has symptoms including emaciation An important gene associated with 3-Hydroxyacyl-Coa Dehydrogenase Deficiency is HADH (Hydroxyacyl-CoA Dehydrogenase). The drugs Naloxone and Buprenorphine have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and skeletal muscle, and related phenotypes are feeding difficulties in infancy and growth delay

2) Glutaric Aciduria Type 1
Glutaric Acidemia I, also known as glutaryl-coa dehydrogenase deficiency, is related to multiple acyl-coa dehydrogenase deficiency and 2-hydroxyglutaric aciduria, and has symptoms including muscle rigidity and opisthotonus. An important gene associated with Glutaric Acidemia I is GCDH (Glutaryl-CoA Dehydrogenase), and among its related pathways/superpathways are Metabolism and Fatty acid metabolism. The drugs Carbamide peroxide and Ornithine have been mentioned in the context of this disorder. Affiliated tissues include brain, caudate nucleus and kidney, and related phenotypes are abnormal enzyme/coenzyme activity and glutaric aciduria

3) Lymphoproliferative Disorders
Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation, also known as autoimmune lymphoproliferative syndrome due to ctla4 haploinsuffiency, is related to pontocerebellar hypoplasia, type 14 and pontocerebellar hypoplasia, type 15, and has symptoms including diarrhea An important gene associated with Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation is CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4). The drugs Basiliximab and Hematinics have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, t cells and lung, and related phenotypes are splenomegaly and hepatomegaly

4) Charcot-Marie-Tooth Disease, Type 2
Charcot-Marie-Tooth Disease, Axonal, Type 2e, also known as charcot-marie-tooth disease type 2, is related to charcot-marie-tooth disease, axonal, type 2j and charcot-marie-tooth disease, axonal, type 2t. An important gene associated with Charcot-Marie-Tooth Disease, Axonal, Type 2e is IGHMBP2 (Immunoglobulin Mu DNA Binding Protein 2), and among its related pathways/superpathways are Cytoskeletal Signaling and tRNA Aminoacylation. Affiliated tissues include skeletal muscle, heart and cortex, and related phenotypes are upper limb muscle weakness and peripheral axonal neuropathy

The "AASS Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AASS comprehensively including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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