LINC02145: A Long Intergenic Non-Protein-Coding RNA as a Drug Target and Biomarker

Target Name: LINC02145

NCBI ID: G401172

LINC02145

Other Name(s): long intergenic non-protein coding RNA 2145 | Long intergenic non-protein coding RNA 2145

LINC02145: A Long Intergenic Non-Protein-Coding RNA as a Drug Target and Biomarker

LINC02145 is a long non-coding RNA (lncRNA) that has been identified in various studies as having important functional roles in various organisms, including humans. This RNA has been shown to play a key role in the regulation of gene expression and has been associated with various diseases, including cancer, neurodegenerative diseases, and developmental disorders. As a result, LINC02145 has gained significant interest as a potential drug target and biomarker.

Disease-Related Function of LINC02145

LINC02145 has been shown to be involved in the regulation of gene expression in various diseases. For example, studies have shown that LINC02145 is downregulated in various cancer types, including breast, ovarian, and colorectal cancers. This downregulation has been associated with the development of cancer stem cells, which are responsible for the persistent and metastatic properties of these diseases.

In addition to its role in cancer, LINC02145 has also been shown to be involved in the regulation of neurodegenerative diseases. For example, studies have shown that LINC02145 is involved in the regulation of gene expression in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. The loss of LINC02145 has been shown to contribute to the development and progression of these diseases.

Furthermore, LINC02145 has also been associated with various developmental disorders. Studies have shown that LINC02145 plays a key role in the regulation of gene expression in developing organisms, including humans. The loss of LINC02145 has been shown to contribute to the development and progression of various developmental disorders, including Down syndrome and Fragile X syndrome.

Potential Drug Target

The potential drug target for LINC02145 is based on its role in the regulation of gene expression and its association with various diseases. LINC02145 has been shown to play a key role in the regulation of gene expression in cancer, neurodegenerative diseases, and developmental disorders. As a result, LINC02145 has the potential to be a drug target for the treatment of these diseases.

One approach to targeting LINC02145 as a drug target is to use small molecules or antibodies to inhibit its activity. This can be done by targeting specific regions of LINC02145 that are involved in its function, such as its binding to a protein or its role in the regulation of gene expression.

Another approach to targeting LINC02145 as a drug target is to use drugs that specifically target its downstream targets. For example, drugs that inhibit the activity of LINC02145-regulated proteins can be used to target LINC02145 directly.

Biomarker

LINC02145 has also been shown to be a potential biomarker for various diseases. For example, studies have shown that LINC02145 is downregulated in various cancer types, including breast, ovarian, and colorectal cancers. This downregulation has been associated with the development of cancer stem cells, which are responsible for the persistent and metastatic properties of these diseases.

In addition to its role in cancer, LINC02145 has also been shown to be involved in the regulation of gene expression in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. The loss of LINC02145 has been shown to contribute to the development and progression of these diseases.

Furthermore, LINC02145 has also been associated with various developmental disorders. Studies have shown that LINC02145 plays a key role in the regulation of gene expression in developing organisms, including humans. The loss of LINC02145 has been shown to contribute to the development and progression of various developmental disorders, including Down syndrome and Fragile X syndrome.

Conclusion

In conclusion, LINC02145 is a long non-coding RNA that has significant interest as a potential drug target and biomarker. Its role in the regulation of gene expression and its association with various diseases make it an attractive target for drug development. Further research is needed to fully understand the function of LINC02145 and its potential as a drug

Protein Name: Long Intergenic Non-protein Coding RNA 2145

The "LINC02145 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC02145 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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