Target Name: MIR378A
NCBI ID: G494327
Review Report on MIR378A Target / Biomarker Content of Review Report on MIR378A Target / Biomarker
MIR378A
Other Name(s): miRNA378 | MIRN378 | Mirn378 | hsa-mir-378a | MIR378 | MicroRNA 378a | microRNA 378a | hsa-miR-378a-3p | hsa-miR-378a-5p | hsa-mir-378

MIR378A: A promising drug target and biomarker for cancer

MiRNA molecules are small RNA molecules in cells that have the function of inhibiting gene expression. In cancer, abnormal expression of miRNA molecules is an important cause of tumorigenesis. Therefore, it is of great significance to study the application of miRNA molecules in cancer treatment. In recent years, researchers have discovered that miRNA378A is abnormally expressed in a variety of cancers and plays an important role in drug screening and tumor treatment. This article will introduce miRNA378A in detail and explore its potential and research direction as a drug target or tumor biomarker.

Expression of miRNA378A

miRNA378A is a 200-nucleotide-long miRNA molecule that originally originated during embryonic development. In adult tissues, the expression level of miRNA378A is very low, but in some types of cancer, the expression level of miRNA378A is significantly increased.

Studies have shown that miRNA378A is abnormally expressed in a variety of cancers, including lung cancer, liver cancer, breast cancer, and ovarian cancer. In these cancers, the expression level of miRNA378A is closely related to cancer prognosis and treatment response.

Drug target potential of miRNA378A

As an emerging drug target, miRNA378A has important potential in cancer treatment. First, miRNA378A can be used as a target for tumor treatment because it is highly expressed in tumor tissues. Secondly, miRNA378A can serve as a tumor biomarker because its expression changes with tumor development.

Tumor therapeutic effect of miRNA378A

Research shows that miRNA378A can inhibit the growth and spread of tumor tissue and has significant efficacy in tumor treatment. For example, studies have found that miRNA378A inhibitors can significantly inhibit tumor growth and spread of lung and liver cancers, and can extend the survival time of patients.

Tumor biomarker application of miRNA378A

miRNA378A can serve as a tumor biomarker because its expression changes with tumor development. The increase in the expression level of miRNA378A is closely related to the progression and invasion of tumors. Therefore, miRNA378A can be used as an important indicator to monitor disease progression after tumor treatment.

Biological mechanism of miRNA378A

The biological mechanism of miRNA378A is unclear, but studies have shown that miRNA378A can affect tumor occurrence and development in multiple ways. First, miRNA378A can bind to proteins in tumor cells, thereby inhibiting their growth and spread. Secondly, miRNA378A can regulate

Protein Name: MicroRNA 378a

The "MIR378A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR378A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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