AADAT: A Potential Drug Target Or Biomarker for Various Diseases

Target Name: AADAT

NCBI ID: G51166

AADAT

AADAT: A Potential Drug Target Or Biomarker for Various Diseases

AADAT (Aspartic Acid-Conjugated Adenylate Carrier Protein) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a carrier protein that transports adenylate, a molecule that plays a critical role in various cellular processes, including metabolism and signaling.

Recent studies have identified AADAT as a potential drug target or biomarker for various diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders.

One of the reasons for the interest in AADAT is its role in the regulation of energy metabolism. Adenylate is a precursor to nitric oxide, a molecule that relaxes blood vessels and improves blood flow. By carrying adenylate across the cell membrane, AADAT helps to maintain the proper balance of nitric oxide in the body.

In addition to its role in energy metabolism, AADAT has also been shown to play a role in the regulation of cellular signaling pathways. It has been shown to interact with various signaling molecules, including nitric oxide, insulin, and angiotensin II. This suggests that AADAT may be involved in the regulation of cellular processes that are important for overall health and disease.

Another potential drug target for AADAT is its role in the development and progression of neurodegenerative disorders. Studies have shown that AADAT is expressed in the brains of individuals with neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. Additionally, AADAT has been shown to interact with various neurotransmitters that are involved in the development and progression of these disorders.

In addition to its potential drug target and biomarker properties, AADAT has also been shown to have potential therapeutic applications in other areas. For example, AADAT has been shown to have anti-inflammatory effects, which may make it a useful agent for the treatment of inflammatory disorders. Additionally, AADAT has been shown to have antioxidant properties, which may make it a useful agent for the treatment of oxidative stress-related diseases.

Overall, AADAT is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Its role in energy metabolism and cellular signaling pathways, as well as its potential therapeutic applications in neurodegenerative disorders and other areas, make it an attractive target for further research and development.

Protein Name: Aminoadipate Aminotransferase

Functions: Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro)

The "AADAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AADAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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