LTB4R2 Regulates JAK/STAT Signaling Pathway (G56413)

Target Name: LTB4R2

NCBI ID: G56413

LTB4R2

LTB4R2 Regulates JAK/STAT Signaling Pathway

LTB4R2 (LTB4 receptor JULF2) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a member of the JAK/STAT signaling pathway, which is a well-established pathway for the regulation of cellular responses to various signaling molecules, including tyrosine and chemokines. This pathway is involved in the regulation of a wide range of physiological processes, including inflammation, stress responses, and metabolism.

The JAK/STAT signaling pathway is activated by the recruitment of STAT3, a protein that is downstream of the JAK protein. This protein is composed of two subunits, JAK and STAT3, which are farnesylated and activated by the presence of tyrosine. The recruitment of STAT3 to the JAK protein is a critical event that allows for the downstream regulation of many cellular processes.

LTB4R2 is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a member of the JAK/STAT signaling pathway, which is a well-established pathway for the regulation of cellular responses to various signaling molecules, including tyrosine and chemokines. This pathway is involved in the regulation of a wide range of physiological processes, including inflammation, stress responses, and metabolism.

The JAK/STAT signaling pathway is activated by the recruitment of STAT3, a protein that is downstream of the JAK protein. This protein is composed of two subunits, JAK and STAT3, which are farnesylated and activated by the presence of tyrosine. The recruitment of STAT3 to the JAK protein is a critical event that allows for the downstream regulation of many cellular processes.

One of the functions of LTB4R2 is to regulate the activity of the JAK/STAT signaling pathway. This is accomplished through the interaction between LTB4R2 and STAT3. This interaction allows for the inhibition of the activity of STAT3, which is downstream of the JAK protein. This inhibition of STAT3 activity can result in the downstream regulation of many cellular processes, including inflammation, stress responses, and metabolism.

In addition to its role in the regulation of the JAK/STAT signaling pathway, LTB4R2 is also involved in the regulation of cellular processes that are independent of the JAK/STAT pathway. This includes the regulation of inflammation, stress responses, and metabolism.

One of the functions of LTB4R2 is to regulate the activity of the JAK/STAT signaling pathway. This is accomplished through the interaction between LTB4R2 and STAT3. This interaction allows for the inhibition of the activity of STAT3, which is downstream of the JAK protein. This inhibition of STAT3 activity can result in the downstream regulation of many cellular processes, including inflammation, stress responses, and metabolism.

Another function of LTB4R2 is to regulate the expression of other genes that are involved in the regulation of cellular processes. This includes the regulation of genes that are involved in the regulation of inflammation, stress responses, and metabolism.

The JAK/STAT signaling pathway is a well-established pathway for the regulation of cellular responses to various signaling molecules, including tyrosine and chemokines. The recruitment of STAT3 to the JAK protein is a critical event that allows for the downstream regulation of many cellular processes. The regulation of these processes by LTB4R2 is accomplished through the interaction between LTB4R2 and STAT3, which allows for the inhibition of the activity of STAT3.

Protein Name: Leukotriene B4 Receptor 2

Functions: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3

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