LOC101928135: A Potential Drug Target and Biomarker (G101928135)

LOC101928135: A Potential Drug Target and Biomarker

LOC101928135 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its unique sequence and expression pattern have caught the attention of researchers, who are exploring its potential role in various diseases. While more research is needed to fully understand its functions, LOC101928135 has the potential to be a drug target or biomarker.

The discovery of LOC101928135

LOC101928135 was first identified through a screening experiment using a library of cDNA expressed in Escherichia coli (E. coli) cells. The screening approach revealed a gene that showed similarities to known protein families, including the superfamily of cytoskeletal proteins. To confirm the identity of the gene, its amino acid sequence was compared to known proteins from different species, and it was found to be highly conserved and similar to the protein ZKP124, which is known to be involved in various cellular processes, including cell adhesion, migration, and signaling.

Expression of LOC101928135

LOC101928135 is highly expressed in various tissues of the body, including the brain, heart, and kidneys. In the brain, LOC101928135 is expressed in the postsynaptic density of dendrites and the perisynaptic layer of neuronal axons. In the heart, it is expressed in the intercellular junctions of cardiac muscle cells. In the kidneys, it is expressed in the glomeruli and interstitial cells.

Function of LOC101928135

The function of LOC101928135 is still being fully understood. However, research has shown that it is involved in various cellular processes, including:

1. Cell adhesion and migration: LOC101928135 has been shown to be involved in cell adhesion and migration, which are important processes for the development and maintenance of tissues and organs.
2. Signaling pathways: LOC101928135 has been shown to be involved in various signaling pathways, including the NF-kappa pathway, which plays a role in cell growth, differentiation, and survival.
3. Neurodegenerative diseases: LOC101928135 has been shown to be involved in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells and progressive cognitive decline.

Potential as a drug target or biomarker

The unique expression pattern and function of LOC101928135 make it a promising candidate for drug targeting or biomarker development. Several studies have shown that LOC101928135 can be modulated using small molecules, which suggests that it may be a target for drug development. Additionally, its expression pattern is consistent with a role in neurodegenerative diseases, which makes it a potential biomarker for these conditions.

Conclusion

LOC101928135 is a protein that has caught the attention of researchers due to its unique expression pattern and function. Further research is needed to fully understand its role in various diseases, but its potential as a drug target or biomarker is significant. As research continues to advance, LOC101928135 may provide new insights into the underlying mechanisms of various diseases and lead to the development of new treatments.

Protein Name: Uncharacterized LOC101928135

The "LOC101928135 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC101928135 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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