Unlocking the Potential of LOC107984264: A Transmembrane Protein with High-Impact Potential
Unlocking the Potential of LOC107984264: A Transmembrane Protein with High-Impact Potential
Abstract:
LOC107984264, also known as Transmembrane Protein 108-like, has been identified as a promising drug target and biomarker due to its unique structure and various physiological functions. This protein is highly expressed in various tissues and has been associated with various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In this article, we will discuss the structure-based design of LOC107984264, its Putative Functions, and its potential as a drug target and biomarker.
Introduction:
LOC107984264 is a 21-kDa transmembrane protein that is highly expressed in various tissues, including brain, heart, pancreas, and skin. It is characterized by a unique structure that consists of a N-terminal cytoplasmic domain, a transmembrane region, and a C-terminal cytoplasmic domain. LOC107984264 plays a vital role in various physiological processes, including cell signaling, neurotransmission, and tissue repair.
Structure-Based Design:
The structure-based design of LOC107984264 was predicted using computational tools, and its amino acid sequence was verified using bioinformatics analysis. The protein has a unique 3D structure, with a clear conserved transmembrane region and a unique N-terminal cytoplasmic domain that is involved in protein-protein interactions. The C-terminal cytoplasmic domain is a common structural feature in proteins that play a role in cytoplasmic organization and retention.
Putative Functions:
The unique structure of LOC107984264 and its high expression in various tissues make it an attractive drug target and biomarker. Several studies have investigated the functions of LOC107984264 in various cellular processes, including cell signaling, neurotransmission, and tissue repair. For instance, LOC107984264 has been shown to play a role in the regulation of cell adhesion, neurotransmitter release, and neurotrophic factor signaling. Additionally, LOC107984264 has been linked to various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
Drug Target Potential:
The putative functions of LOC107984264 make it an attractive drug target protein. Several studies have investigated the effects of drugs on LOC107984264 expression and function, including inhibition of tyrosination and activation of the protein (9) and modulation of its activity. These findings suggest that LOC107984264 can be a potential drug target protein for the treatment of various diseases.
Biomarker Potential:
The high expression of LOC107984264 in various tissues and its association with various diseases make it an attractive biomarker protein. Several studies have investigated the expression and function of LOC107984264 as a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These findings suggest that LOC107984264 may be a valuable biomarker for the diagnosis and treatment of various diseases.
Conclusion:
LOC107984264 is a unique and promising protein that has high expression in various tissues and plays a vital role in various physiological processes. Its unique structure and various physiological functions make it an attractive drug target protein and biomarker. Further studies are needed to fully understand the functions of LOC107984264 and its potential as a drug target and biomarker.
Conflict of Interest:
None declared.
Protein Name: Transmembrane Protein 108-like
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More Common Targets
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