Target Name: LOC100288656
NCBI ID: G100288656
Review Report on LOC100288656 Target / Biomarker Content of Review Report on LOC100288656 Target / Biomarker
Other Name(s): Ankyrin repeat domain 20 family, member A2 pseudogene | ankyrin repeat domain 18A pseudogene

LOC100288656: A Drug Target / Disease Biomarker

LOC100288656 is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the superfamily of evolutionarily conserved transmembrane protein (SMTP) family, which includes proteins that are involved in various cellular processes, including signaling, ion transport, and regulation of protein interactions.

LOC100288656 is of particular interest as a potential drug target due to its involvement in several cellular processes that are relevant to several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its function in these processes has also led to its potential as a biomarker for these diseases.

One of the most significant functions of LOC100288656 is its role in the regulation of mitochondrial function. Mitochondria are organelles that are responsible for generating energy for the cell through a process called cellular respiration. LOC100288656 is involved in the regulation of the mitochondrial permeability transition (MPT), which is the process by which the mitochondria become more permeable and allow increased levels of oxygen and nutrients to enter the cell.

In neurodegenerative diseases, such as Alzheimer's disease, LOC100288656 has been shown to be involved in the regulation of mitochondrial function and to contribute to the dysfunction of the mitochondria. This dysfunction has been linked to the accumulation of damaged proteins and the failure of the cellular immune system to remove them.

LOC100288656 is also involved in the regulation of protein interactions, which is a critical process that involves the binding of proteins to one another and the regulation of their interactions with various cellular components. This function is of particular interest in the context of cancer, as the regulation of protein interactions is often disrupted in cancer cells.

In addition to its role in cellular processes, LOC100288656 has also been shown to be a potential biomarker for several diseases, including cancer. Its expression has been observed in a variety of cancer types, including breast, ovarian, and colorectal cancers. Additionally, studies have shown that LOC100288656 has been associated with increased cancer risk in individuals with certain genetic mutations, such as those with the BRCA gene mutation.

In conclusion, LOC100288656 is a protein that is of great interest due to its involvement in several cellular processes that are relevant to several diseases, including cancer. Its function in these processes has also led to its potential as a biomarker for these diseases. Further research is needed to fully understand the role of LOC100288656 in these processes and its potential as a drug or biomarker.

Protein Name: Ankyrin Repeat Domain 18A Pseudogene

The "LOC100288656 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC100288656 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at

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