IL-8 Plays A Crucial Role in Immune Response and Inflammation

Target Name: IGHVIII-22-2

NCBI ID: G28349

IGHVIII-22-2

Other Name(s): 3-22.2P | immunoglobulin heavy variable (III)-22-2 (pseudogene) | IGHVIII222 | Immunoglobulin heavy variable (III)-22-2 (pseudogene)

IL-8 Plays A Crucial Role in Immune Response and Inflammation

IGHVIII-22-2 (3-22.2P), also known as human interleukin-8 (IL-8), is a cytokine that plays a crucial role in the immune response and inflammation. It is a member of the interleukin family, which consists of nine cytokines that regulate various cellular processes in the body, including immune function, cell signaling, and inflammation.

IL-8 is a type-I transmembrane protein that is expressed in a variety of tissues and cells, including epithelial, endothelial, and immune cells. It is a potent chemoattractant for immune cells, such as neutrophils, and has been shown to play a key role in the recruitment and activation of these cells during inflammation.

IL-8 is involved in the regulation of cellular processes that are critical for immune function, including the recruitment and activation of immune cells, the production of pro-inflammatory cytokines, and the regulation of cellular apoptosis. It is a potent mediator of inflammation and has been shown to play a key role in the pathogenesis of a variety of diseases, including cancer, autoimmune diseases, and chronic obstructive pulmonary disease (COPD).

IL-8 has also been shown to be a potential drug target and biomarker for a variety of diseases. For example, it has been shown to be a potential therapeutic agent for cancer, including breast, ovarian, and colorectal cancers. In addition, IL-8 has been shown to be a potential biomarker for a variety of autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis.

IL-8 has also been shown to be involved in the regulation of cellular processes that are critical for the development and progression of chronic obstructive pulmonary disease (COPD). Studies have shown that IL-8 is involved in the regulation of airway epithelial cell function, matrix metalloproteinase (MMP) expression, and surfactant production, all of which are critical for the development of COPD.

In addition to its role in the immune response and inflammation, IL-8 is also involved in the regulation of cellular processes that are critical for the development and progression of various diseases, including cancer, autoimmune diseases, and COPD. Its potential as a drug target and biomarker make it an attractive target for research and development of new treatments for these diseases.

Protein Name: Immunoglobulin Heavy Variable (III)-22-2 (pseudogene)

The "IGHVIII-22-2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IGHVIII-22-2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets