LINC00642: A Long Intergenic Non-Protein Coding RNA (G400238)

Target Name: LINC00642

NCBI ID: G400238

LINC00642

Other Name(s): long intergenic non-protein coding RNA 642 | Long intergenic non-protein coding RNA 642

LINC00642: A Long Intergenic Non-Protein Coding RNA

Introduction

LINC00642 is a long non-coding RNA (lncRNA) that has been identified in various genomes. It is characterized by its unique 3' end, which is composed of a stem-loop and a loop-like structure. LINC00642 is different from other lncRNAs in that it does not encode any protein, which is why it is also referred to as a non-protein coding RNA (NPRNA). Despite its non-protein-coding nature, LINC00642 has been shown to play a critical role in various cellular processes , including cell growth, differentiation, and RNA processing.

Molecular Characterization

The full-length sequence of LINC00642 is approximately 290 nucleotides long and has a 3' end that is composed of a stem-loop and a loop-like structure. The stem-loop region is composed of 15 nucleotides and the loop-like region is composed of 9 nucleotides. The overall structure of LINC00642 is highly conserved across different organisms, which suggests that it may have a conserved function.

Expression and Localization

LINC00642 is highly expressed in various tissues and organs, including brain, heart, and muscle. It is also expressed in various cell types, including stem cells, progenitor cells, and differentiated cells. LINC00642 is predominantly expressed in the brain, where it is highly expressed in the prefrontal cortex, an area that is involved in various cognitive functions.

Function and Potential Therapeutic Applications

Several studies have suggested that LINC00642 may have a role in various cellular processes. LINC00642 has been shown to play a critical role in cell growth and differentiation. It has been shown to promote the growth of various cell types, including stem cells and progenitor cells. LINC00642 has also been shown to play a critical role in the regulation of cellular processes, including cell cycle progression and apoptosis.

In addition to its role in cell growth and differentiation, LINC00642 has also been suggested as a potential therapeutic target for various diseases. For example, LINC00642 has been shown to be downregulated in various diseases, including cancer, which suggests that it may have a potential role in these targeting diseases. Additionally, LINC00642 has been shown to be involved in the regulation of various signaling pathways, including the TGF-β pathway. This suggests that LINC00642 may have a potential role in targeting diseases that are associated with disruptions in this pathway.

Conclusion

In conclusion, LINC00642 is a long non-coding RNA that has been identified in various genomes. It is characterized by its unique 3' end, which is composed of a stem-loop and a loop-like structure. LINC00642 is different from other lncRNAs in that it does not encode any protein, which is why it is also referred to as a non-protein coding RNA (NPRNA). Despite its non-protein-coding nature, LINC00642 has been shown to play a critical role in various cellular processes , including cell growth, differentiation, and RNA processing. Its highly expressed in various tissues and cells, and its potential role as a drug target or biomarker make it an interesting target for future research.

Protein Name: Long Intergenic Non-protein Coding RNA 642

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