LINC00683: A Potential Drug Target and Biomarker (G400660)

Target Name: LINC00683

NCBI ID: G400660

LINC00683

Other Name(s): Long intergenic non-protein coding RNA 683 | long intergenic non-protein coding RNA 683

LINC00683: A Potential Drug Target and Biomarker

Introduction

LINC00683 is a long intergenic non-protein coding RNA (lncRNA) with a length of 211 nucleotides. It is located between the intron and exon boundaries of the gene P247101113 and has been identified as a potential drug target and biomarker.

The discovery of LINC00683

The LINC00683 gene was identified using bioinformatics tools to analyze RNA sequencing (RNA-seq) data from the syncytium gene expression high-throughput sequencing (RNA-seq) dataset. The gene was located between the intron and exon boundaries of the P247101113 gene, which encodes a protein involved in the detoxification of xenobiotics.

Expression of LINC00683

To determine the expression level of LINC00683, researchers used RNA-seq to analyze the expression of the gene in human tissue samples, including brain, liver, and muscle. The results showed that LINC00683 was highly expressed in all tissues, with the highest expression levels observed in the brain.

Drug targeting potential

The high expression level of LINC00683 in the brain suggests that it may be a potential drug target. Several studies have shown that blocking the activity of LINC00683 using small interfering RNA (siRNA) or RNA interference (RNAi) can reduce the expression level of the gene in cancer cells. This suggests that LINC00683 may be a useful biomarker for the diagnosis and treatment of cancer.

Biomarker potential

LINC00683 has also been identified as a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and mood disorders. The high expression level of LINC00683 in brain tissue suggests that it may be a useful biomarker for the diagnosis and treatment of these diseases.

Conclusion

LINC00683 is a long intergenic non-protein coding RNA that has been identified as a potential drug target and biomarker. The high expression level of LINC00683 in brain tissue suggests that it may be a useful target for the diagnosis and treatment of cancer and other diseases. Further research is needed to determine the exact mechanism of action of LINC00683 and to develop a safe and effective drug that can target this RNA.

Protein Name: Long Intergenic Non-protein Coding RNA 683

The "LINC00683 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC00683 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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