Target Name: MIR27A
NCBI ID: G407018
Review Report on MIR27A Target / Biomarker Content of Review Report on MIR27A Target / Biomarker
MIR27A
Other Name(s): microRNA 27a | hsa-miR-27a-3p | hsa-miR-27a-5p | MIR27 | MicroRNA 27a | mir-27a | MIRN27A | hsa-mir-27a

MIR27a: A Non-Coding RNA Molecule Regulating Cellular Processes

MicroRNA (miRNA) 27a is a non-coding RNA molecule that plays a crucial role in regulating various cellular processes in the body. It is made up of 20 amino acid residues and has a unique structure that consists of a hairpin loop and a stem- loop. MIR27a is expressed in most tissues of the body and is involved in a wide range of cellular processes, including cell growth, differentiation, and apoptosis.

One of the unique features of MIR27a is its ability to interact with other molecules. It can form double-stranded RNA structures with various partner proteins, including microtubules of the mitotic spindle. These interactions play a critical role in the regulation of mitotic spindle dynamics and the proper assembly of the spindle fibers.

MIR27a is also known for its role in the regulation of cell cycle progression. It has been shown to play a negative role in the regulation of G1 phase and has been shown to promote the G2/M phase. This means that MIR27a promotes the transition from the G1 phase to the M phase of the cell cycle, which is when the cell prepares for cell division.

MIR27a is also involved in the regulation of cellular apoptosis. It has been shown to play a critical role in the regulation of apoptosis in various cell types, including neurons and cancer cells. MIR27a has been shown to interact with the Bcl-2 protein, which is a protein that can prevent apoptosis. By interacting with Bcl-2, MIR27a can inhibit the activity of Bcl-2 and prevent the regulation of apoptosis.

MIR27a is also involved in the regulation of stem cell proliferation. It has been shown to play a critical role in the regulation of stem cell proliferation, and it has been shown to be involved in the process of self-renewal of stem cells. has been shown to interact with the transcription factor, p53, and to play a role in the regulation of the p53 response element.

MIR27a is also involved in the regulation of inflammation. It has been shown to play a critical role in the regulation of inflammation, and it has been shown to be involved in the process of immune response. MIR27a has been shown to interact with the transcription factor , NF-kappa-B, and to play a role in the regulation of the NF-kappa-B response element.

MIR27a is also involved in the regulation of tissue repair. It has been shown to play a critical role in the regulation of tissue repair, and it has been shown to be involved in the process of wound healing. MIR27a has been shown to interact with the Transcription factor, transforming growth factor, TGF-β, and to play a role in the regulation of the TGF-β response element.

MIR27a is also involved in the regulation of the blood-brain barrier. It has been shown to play a critical role in the regulation of the blood-brain barrier, and it has been shown to be involved in the process of brain development and function. MIR27a has been shown to interact with the transmembrane protein, Aquaporin (AQP), and to play a role in the regulation of AQP expression.

In conclusion, MIR27a is a microRNA that plays a crucial role in regulating various cellular processes in the body. Its unique structure and ability to interact with other molecules make it an attractive drug target and a potential biomarker. Further research is needed to fully understand the role of MIR27a in cellular processes and to develop effective treatments for the prevention and treatment of various diseases.

Protein Name: MicroRNA 27a

The "MIR27A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR27A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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