Target Name: AAR2
NCBI ID: G25980
Review Report on AAR2 Target / Biomarker Content of Review Report on AAR2 Target / Biomarker
AAR2
Other Name(s): OTTHUMP00000030846 | AAR2_HUMAN | AAR2 splicing factor homolog | DKFZp564N1363 | Uncharacterized protein C20orf4 | AAR2 splicing factor | bA234K24.2 | C20orf4 | CGI-23 | AAR2 variant 1 | Protein AAR2 homolog

AAR2: Key Regulator of Cellular Processes and Potential Drug Target

AAR2 (OTTHUMP00000030846) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of AAR2 is its role in the regulation of cell proliferation. It is a transcription factor that interacts with DNA to control the expression of genes that are involved in cell growth and division. This includes the regulation of the production of proteins that are involved in cell adhesion, migration, and invasion, as well as the regulation of cell apoptosis, or programmed cell death.

In addition to its role in cell proliferation, AAR2 is also involved in the regulation of cell survival. It has been shown to play a key role in the regulation of cellular stress responses, which are critical for the survival of cells under conditions of cellular stress, such as those that are exposed to environmental toxins or that are undergoing stress due to disease.

AAR2 has also been shown to be involved in the regulation of inflammation. It has been shown to play a key role in the regulation of the immune response, and is involved in the regulation of the production of pro-inflammatory cytokines. This includes the regulation of the production of TNF-alpha, a cytokine that is involved in inflammation and autoimmune disorders.

In addition to its role in inflammation, AAR2 has also been shown to be involved in the regulation of cellular signaling pathways. It has been shown to play a key role in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cell survival and proliferation.

Despite its involvement in a number of important cellular processes, AAR2 is not yet a well-studied protein. There are currently limited studies that have investigated its role in disease, and more research is needed to fully understand its function and potential as a drug target.

One potential drug target for AAR2 is the inhibition of its activity. This could be done through a variety of methods, including the use of small molecules, antibodies, or genetic modifiers. The use of these approaches could help to identify new treatments for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Another approach to studying AAR2 is through the use of RNA interference (RNAi) technology. This is a technique that allows researchers to introduce small interfering RNA (siRNA) into cells in order to knockdown the expression of specific genes. By using RNAi to knockdown the expression of AAR2, researchers can study its function and potential as a drug target.

Overall, AAR2 is a protein that is involved in a number of important cellular processes and has been implicated in a variety of diseases. Further research is needed to fully understand its function and potential as a drug target. The inhibition of its activity through the use of small molecules, antibodies, or genetic modifiers, or through the use of RNAi technology, could lead to new treatments for a variety of diseases.

Protein Name: AAR2 Splicing Factor

Functions: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing

The "AAR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AAR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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