Target Name: MIR377
NCBI ID: G494326
Review Report on MIR377 Target / Biomarker Content of Review Report on MIR377 Target / Biomarker
MIR377
Other Name(s): MicroRNA 377 | hsa-miR-377-3p | hsa-miR-377-5p | hsa-mir-377 | microRNA 377 | mir-377 | MIRN377

Discovering MIR377: A Potential Drug Target and Biomarker

MicroRNA (miRNA) 377 (MIR377) is a non-coding RNA molecule that plays a critical role in various biological processes. MIR377 is a member of the 21 non-coding RNA family, which are known as miRNAs. These molecules are approximately 20-22 nucleotides in length and are found in various cell types. MIR377 is unique due to its specific structure and its role in the development and progression of various diseases.

The discovery and characterization of MIR377 was made by a research team led by Dr. Yueh-Hua Zhou at the University of California, San Diego. The team identified MIR377 as a potential drug target and potential biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders.

MIR377 is a highly conserved molecule that is found in various cell types, including human brain, heart, and muscle cells. It is expressed in high levels in cancer cells and has been implicated in the development and progression of various diseases. MIR377 has been shown to play a role in the regulation of various cellular processes, including cell growth, apoptosis (programmed cell death), and inflammation.

One of the most significant functions of MIR377 is its role in cell apoptosis. MIR377 has been shown to promote the apoptosis of cancer cells, which is a natural process that helps remove damaged or dysfunctional cells from the body. This process is important for maintaining tissue homeostasis and for preventing the formation of cancer tumors.

MIR377 has also been shown to play a role in the regulation of cell growth. It has been shown to inhibit the growth of human cancer cells and to promote the growth of normal tissues. This suggests that MIR377 may be a useful drug target for cancer treatments.

In addition to its role in cell apoptosis and growth, MIR377 has also been shown to play a role in inflammation. It has been shown to regulate the production of pro-inflammatory cytokines, which are important drivers of inflammation. This suggests that MIR377 may be a useful biomarker for monitoring the severity of inflammatory diseases.

The identification of MIR377 as a potential drug target and biomarker has important implications for the development of new treatments for various diseases. MIR377 has been shown to be a promising target for cancer treatments, with potential applications in both human and animal models of cancer. For example, researchers have shown that inhibiting MIR377 can significantly reduce the growth of human cancer cells in cell culture and animal models of cancer.

In addition to its potential as a cancer drug, MIR377 has also been shown to be a potential biomarker for neurodegenerative diseases. Studies have shown that MIR377 is downregulated in the brains of individuals with neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This suggests that MIR377 may be a useful biomarker for these diseases and may help to identify potential therapeutic targets.

MIR377 has also been shown to play a role in the regulation of various physiological processes in the body, including blood pressure and heart function. Studies have shown that MIR377 is involved in the regulation of blood pressure and heart rate in animal models of hypertension and heart failure. This suggests that MIR377 may be a useful target for treatments of these conditions.

In conclusion, MIR377 is a non-coding RNA molecule that plays a critical role in various biological processes. Its unique structure and its role in the development and progression of various diseases make it an attractive target for drug development and biomarker research. Further studies are needed to fully understand the functions of MIR377 and its potential as a drug

Protein Name: MicroRNA 377

The "MIR377 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR377 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MIR378A | MIR378B | MIR378C | MIR378D1 | MIR378D2 | MIR378E | MIR378F | MIR378G | MIR378H | MIR378I | MIR379 | MIR380 | MIR381 | MIR382 | MIR383 | MIR384 | MIR3907 | MIR3908 | MIR3909 | MIR3910-1 | MIR3910-2 | MIR3911 | MIR3912 | MIR3913-1 | MIR3913-2 | MIR3914-1 | MIR3914-2 | MIR3915 | MIR3916 | MIR3917 | MIR3918 | MIR3919 | MIR3920 | MIR3921 | MIR3922 | MIR3923 | MIR3924 | MIR3925 | MIR3926-1 | MIR3926-2 | MIR3927 | MIR3928 | MIR3929 | MIR3934 | MIR3935 | MIR3936 | MIR3936HG | MIR3937 | MIR3938 | MIR3939 | MIR3940 | MIR3941 | MIR3942 | MIR3943 | MIR3944 | MIR3945 | MIR3945HG | MIR3960 | MIR3972 | MIR3973 | MIR3974 | MIR3976 | MIR3976HG | MIR3977 | MIR3978 | MIR409 | MIR410 | MIR411 | MIR412 | MIR421 | MIR422A | MIR423 | MIR424 | MIR425 | MIR4251 | MIR4252 | MIR4253 | MIR4254 | MIR4255 | MIR4256 | MIR4257 | MIR4258 | MIR4259 | MIR4260 | MIR4261 | MIR4262 | MIR4263 | MIR4264 | MIR4265 | MIR4266 | MIR4267 | MIR4268 | MIR4269 | MIR4270 | MIR4271 | MIR4272 | MIR4273 | MIR4274 | MIR4275 | MIR4276