Target Name: RETSAT
NCBI ID: G54884
Review Report on RETSAT Target / Biomarker Content of Review Report on RETSAT Target / Biomarker
RETSAT
Other Name(s): RETST_HUMAN | retinol saturase | all-trans-13,14-dihydroretinol saturase | Retinol saturase | All-trans-13,14-dihydroretinol saturase | PPAR-alpha-regulated and starvation-induced gene protein | (13,14)-all-trans-retinol saturase | RetSat | FLJ20296 | PPSIG | All-trans-retinol 13,14-reductase precursor | All-trans-retinol 13,14-reductase | All-trans-retinol:all-trans-13,14-dihydroretinol saturase

RetSAT: A Promising Drug Target for Eye Diseases

RetSAT (short for Retinol-conjugated Enhanced Sub-retinal Transfer) is a drug target (also known as a biomarker) that is being studied for its potential to treat a variety of eye diseases, including age-related macular degeneration (AMD), diabetic retinopathy, and cataracts. RetSAT is a form of vitamin A that is designed to be administered directly into the eye, and it has been shown to have potential to slow the progression of these diseases.

One of the main ways that RetSAT works is by increasing the amount of vitamin A that is available to the retina. Vitamin A is a critical macronutrient that is necessary for the health and function of the retina, and it is a key factor in the development and progression of many eye diseases. In particular, vitamin A has been shown to be effective in protecting against the development and progression of cataracts, and it has also been shown to help treat the symptoms of AMD.

In addition to its potential benefits for eye health, RetSAT has also been shown to have potential as a drug target. By targeting the vitamin A receptor (VAR), RetSAT has been shown to be able to inhibit the growth of cancer cells and reduce the formation of blood-vessel-rich scars. This makes it a potential target for the treatment of a variety of cancers, including eye cancer.

While the use of RetSAT as a drug or biomarker is still in its early stages, there is significant potential for it to become a valuable tool in the treatment of eye diseases. With further research, it is likely that RetSAT will be shown to be effective in treating a wide range of eye conditions, including those that are currently treated with limited options.

Overall, RetSAT is a promising drug target and biomarker that has the potential to revolutionize the treatment of eye diseases. While more research is needed to fully understand its potential, it is already clear that RetSAT is a valuable tool in the fight against these conditions.

Protein Name: Retinol Saturase

Functions: Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation

The "RETSAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RETSAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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