Target Name: RGPD5
NCBI ID: G84220
Review Report on RGPD5 Target / Biomarker Content of Review Report on RGPD5 Target / Biomarker
RGPD5
Other Name(s): Ran-binding protein 2-like 1/2 | RanBP2-like 2 | HEL161 | RGPD6 | Sperm membrane protein BS-63 | RanBP2L2 | ran-binding protein 2-like 1 | RANBP2L2 | RGP5 | BS63 | sperm membrane protein BS-63 | RGP6 | RANBP2-like and GRIP domain-containing protein 5/6 | RANBP2-like and GRIP domain-containing protein 5/6 (isoform 1) | RANBP2-like and GRIP domain-containing protein 6 | RGPD7 | epididymis luminal protein 161 | RGPD5_HUMAN | RanBP2-like 1/2 | RanBP2-like 1 | RANBP2 like and GRIP domain containing 5, transcript variant 1 | ran-binding protein 2-like 1/2 | RGP7 | RGPD5 variant 1 | Ran-binding protein 2-like 1 | DKFZp686I1842 | OTTHUMP00000161612 | RANBP2L1 | BS-63 | ranBP2L1 | ranBP2-like 1 | Ran-binding protein 2-like 2 | ranBP2-like 1/2 | RanBP2L1 | RANBP2 like and GRIP domain containing 5 | OTTHUMP00000161611 | RANBP2-like and GRIP domain-containing protein 5

RGPD5: A promising drug target and biomarker for ranvier exclusive

Abstract:

Ran-binding protein 2-like 1/2 (RGPD5) is a protein that plays a crucial role in the regulation of cell growth, apoptosis, and angiogenesis. It is a key regulator of the blood-brain barrier and has been implicated in various neurological disorders. RGPD5 has also been identified as a potential drug target and biomarker. In this article, we will discuss the biology of RGPD5, its functions, its potential as a drug target, and its potential as a biomarker.

Introduction:

Ran-binding protein 2-like 1/2 (RGPD5) is a member of the RGPD5 family, which is characterized by the presence of a nucleotide-binding oligomerization domain (NOD) and a leucine-rich repeat (LRR) domain. RGPD5 is a 21 kDa protein that is expressed in various tissues, including brain, heart, and liver. It plays a crucial role in the regulation of cell growth, apoptosis, and angiogenesis, and has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and colorectal cancer.

biological functions:

RGPD5 is a key regulator in the regulation of cell growth, apoptosis and angiogenesis. It is a key regulator of the blood-brain barrier and is closely associated with a variety of neurological diseases. RGPD5 plays a key role in cell cycle, apoptosis and angiogenesis by binding to leucine-rich repeat domains in the nucleotide and LRR domains. In addition, RGPD5 is also involved in cell-matrix interactions, thereby affecting cell attachment and migration. Activation of RGPD5 leads to cell cycle arrest, apoptosis, and inhibition of angiogenesis, thereby having an important impact on tumor growth and degenerative diseases of the nervous system.

As a drug target:

RGPD5 has attracted extensive research interest as a drug target with potential clinical value. Many studies have shown that RGPD5 inhibitors can inhibit tumor growth and the development of neurodegenerative diseases. For example, a clinical trial showed that inhibiting RGPD5 expression significantly inhibited tumor growth in mice. In addition, RGPD5 inhibitors can inhibit the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Therefore, RGPD5 inhibitors are considered important targets for the future treatment of tumors and neurological diseases.

As a biomarker:

RGPD5 is also a biomarker with potential clinical value. Many studies have shown that RGPD5 expression levels can be used to predict the survival and treatment response of tumor patients. In addition, RGPD5 expression levels can also be used to assess the severity and recovery of neurological diseases. Therefore, RGPD5, as a biomarker, has important clinical value in the diagnosis, treatment and rehabilitation evaluation of tumors and neurological diseases.

in conclusion:

RGPD5 is a protein with potential clinical value and drug target role. It regulates cell cycle, apoptosis and angiogenesis and plays a key role in tumor growth and neurological diseases. RGPD5 inhibitors are considered important targets for future treatment of tumors and neurological diseases. In addition, RGPD5 expression levels can be used as biomarkers to predict survival and treatment response in tumor patients, as well as to assess the severity and recovery of neurological diseases. Therefore, RGPD5 deserves further study as a protein with potential clinical value and drug target role.

Protein Name: RANBP2 Like And GRIP Domain Containing 5

The "RGPD5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RGPD5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RGPD6 | RGPD8 | RGR | RGS1 | RGS10 | RGS11 | RGS12 | RGS13 | RGS14 | RGS16 | RGS17 | RGS18 | RGS19 | RGS2 | RGS20 | RGS21 | RGS22 | RGS3 | RGS4 | RGS5 | RGS6 | RGS7 | RGS7BP | RGS8 | RGS9 | RGS9BP | RGSL1 | RHAG | RHBDD1 | RHBDD2 | RHBDD3 | RHBDF1 | RHBDF2 | RHBDL1 | RHBDL2 | RHBDL3 | RHBG | RHCE | RHCG | RHD | RHEB | RHEBL1 | RHEBP1 | RHEX | RHNO1 | RHO | Rho GTPase | Rho kinase (ROCK) | RHOA | RHOB | RHOBTB1 | RHOBTB2 | RHOBTB3 | RHOC | RHOD | RHOF | RHOG | RHOH | RHOJ | RHOQ | RHOQP3 | RHOT1 | RHOT2 | RHOU | RHOV | RHOXF1 | RHOXF1-AS1 | RHOXF1P1 | RHOXF2 | RHOXF2B | RHPN1 | RHPN1-AS1 | RHPN2 | RIBC1 | RIBC2 | Ribonuclease | Ribonuclease H | Ribonuclease MRP | Ribonuclease P Complex | Ribosomal protein S6 kinase (RSK) | Ribosomal Protein S6 Kinase, 70kDa (p70S6K) | Ribosomal Protein S6 Kinase, 90kDa | Ribosomal subunit 40S | Ribosome-associated complex | RIC1 | RIC3 | RIC8A | RIC8B | RICH1-AMOT complex | RICTOR | RIDA | RIF1 | RIGI | RIIAD1 | RILP | RILPL1 | RILPL2 | RIMBP2 | RIMBP3 | RIMBP3B