Target Name: MIR520C
NCBI ID: G574476
Review Report on MIR520C Target / Biomarker Content of Review Report on MIR520C Target / Biomarker
MIR520C
Other Name(s): hsa-miR-520c-5p | MicroRNA 520c | hsa-mir-520c | MIRN520C | microRNA 520c | hsa-miR-520c-3p

MIR520C: A Potential Drug Target and Biomarker

MicroRNA (miRNA) technology has revolutionized our understanding of gene function and the potential for new therapeutic approaches. One of the most well-studied miRFs is MIR520C, a non-coding RNA molecule that has been shown to play important roles in various cellular processes, including cell growth, differentiation, and metabolism. In this article, we will explore the potential implications of MIR520C as a drug target and biomarker.

MIR520C: Structure and Function

MIR520C is a small non-coding RNA molecule that contains 58 amino acid residues and a unique 3'-end structure composed of a single exon followed by a splice enhancer and a 5'-end cap structure. It is expressed in a variety of tissues , including brain, heart, and muscle, and has been shown to play important roles in various cellular processes. MIR520C is a good candidate for a drug target due to its unique structure, stability, and post-transcriptional modification patterns.

MIR520C has been shown to regulate a variety of cellular processes, including cell growth, apoptosis, and metabolism. One of the most well-studied functions of MIR520C is its role in cell growth. MIR520C has been shown to promote the growth of various cell types , including cancer cells, by regulating the cell proliferation signaling pathway. MIR520C has also been shown to play a role in apoptosis, as it has been shown to induce the apoptosis of cancer cells under certain conditions.

In addition to its functions in cell growth and apoptosis, MIR520C has also been shown to regulate various metabolic processes, including cell energy metabolism and fatty acid oxidation. These functions make MIR520C a promising candidate for a drug target in diseases that involve metabolism dysfunction, such as cancer, obesity, and diabetes.

MIR520C as a Drug Target

The potential of MIR520C as a drug target is due to its unique structure and post-transcriptional modification patterns. MIR520C has a unique 3'-end structure that includes a splice enhancer and a cap structure. This structure allows for the targeted post-transcriptional modification of MIR520C, including phosphorylation and ubiquitination, which can modulate its stability and localization.

MIR520C has also been shown to interact with various protein targets, including the transcription factor NF-kappa-B and the protein tyrosine kinase CREB. These suggest interactions that MIR520C may play a role in regulating cellular processes that are regulated by these factors, including cell growth, apoptosis, and metabolism.

MIR520C has also been shown to be a good biomarker for several diseases, including cancer, neurodegenerative diseases, and metabolic disorders. For example, MIR520C has been shown to be downregulated in various types of cancer, and increasing its expression has been shown to improve the survival of cancer patients. In addition, MIR520C has also been shown to be downregulated in neurodegenerative diseases, such as Alzheimer's disease, and increasing its expression has been shown to improve cognitive function in these conditions. Finally, MIR520C has It has also been shown to be downregulated in metabolic disorders, such as obesity and type 2 diabetes, and increasing its expression has been shown to improve insulin sensitivity and metabolic function.

MIR520C as a Biomarker

MIR520C has also been shown to be a promising biomarker for several diseases, including cancer, neurodegenerative diseases, and metabolic disorders. For example, MIR520C has been shown to be downregulated in various types of cancer, and increasing its expression has been shown to improve the survival of cancer patients. In addition, MIR520C has also been shown to be downregulated in neurodegenerative diseases, such as Alzheimer's disease,

Protein Name: MicroRNA 520c

The "MIR520C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR520C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MIR520D | MIR520E | MIR520F | MIR520G | MIR520H | MIR521-1 | MIR521-2 | MIR522 | MIR523 | MIR524 | MIR525 | MIR526A1 | MIR526A2 | MIR526B | MIR527 | MIR532 | MIR539 | MIR541 | MIR542 | MIR543 | MIR544A | MIR544B | MIR545 | MIR548A1 | MIR548A1HG | MIR548A2 | MIR548A3 | MIR548AA1 | MIR548AA2 | MIR548AC | MIR548AD | MIR548AE1 | MIR548AE2 | MIR548AG1 | MIR548AG2 | MIR548AH | MIR548AI | MIR548AJ1 | MIR548AJ2 | MIR548AL | MIR548AM | MIR548AN | MIR548AO | MIR548AP | MIR548AQ | MIR548AR | MIR548AS | MIR548AT | MIR548AU | MIR548AV | MIR548AW | MIR548AX | MIR548AY | MIR548AZ | MIR548B | MIR548BA | MIR548BC | MIR548C | MIR548D1 | MIR548D2 | MIR548E | MIR548F1 | MIR548F2 | MIR548F3 | MIR548F4 | MIR548F5 | MIR548G | MIR548H1 | MIR548H2 | MIR548H3 | MIR548H4 | MIR548H5 | MIR548I1 | MIR548I2 | MIR548I3 | MIR548I4 | MIR548J | MIR548K | MIR548L | MIR548M | MIR548N | MIR548O | MIR548O2 | MIR548P | MIR548Q | MIR548S | MIR548T | MIR548U | MIR548V | MIR548W | MIR548X | MIR548Y | MIR549A | MIR550A1 | MIR550A2 | MIR550A3 | MIR550B1 | MIR550B2 | MIR551A | MIR551B