LINC01881: A Potential Drug Target and Biomarker (G728323)

Target Name: LINC01881

NCBI ID: G728323

LINC01881

Other Name(s): Long intergenic non-protein coding RNA 1881 | long intergenic non-protein coding RNA 1881

LINC01881: A Potential Drug Target and Biomarker

LINC01881 is a non-coding RNA (ncRNA) molecule that has been identified using RNA-seq technology. It is located within the genic region of the gene ATP1A2, which encodes the protein Bel1.1. Bel1.1 is a key regulator of the cell cycle and has been implicated in various cellular processes, including cell growth, apoptosis, and neurodegeneration. The RNA-seq data has revealed that LINC01881 is highly expressed in various tissues and cells, including brain, pancreas, and peripheral blood mononuclear cells.

Drug Target Potential

The potential drug target for LINC01881 is its role in the regulation of the cell cycle. The over-expression of LINC01881 has been shown to result in an increase in the number of cells in the G1 phase, which is associated with the regulation of cell cycle progression. Additionally, LINC01881 has been shown to play a role in the regulation of mitosis, as it has been shown to promote the formation of sister chromatids during interphase.

Biomarker Potential

LINC01881 has also been shown to be a potential biomarker for various diseases, including cancer. The increased expression of LINC01881 has been observed in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, LINC01881 has been shown to be downregulated in cancer cells, which may indicate that it could be a potential therapeutic target.

Expression and Localization

LINC01881 is highly expressed in various tissues and cells, including the brain, pancreas, and peripheral blood mononuclear cells. It has been shown to be expressed in the nuclei of these cells and to localize to the nuclear envelope.

Function and Interaction

The function of LINC01881 is not well understood, but its expression and localization suggest that it may be involved in the regulation of various cellular processes. It is possible that LINC01881 functions as a negative regulator of the cell cycle, as its over-expression has been shown to increase the number of cells in the G1 phase. Additionally, LINC01881 may be involved in the regulation of mitosis, as it has been shown to promote the formation of sister chromatids during interphase.

Conclusion

In conclusion, LINC01881 is a non-coding RNA molecule that has been identified using RNA-seq technology. Its expression and localization suggest that it may be involved in the regulation of various cellular processes, including the cell cycle and mitosis. The potential drug target for LINC01881 is its role in the regulation of the cell cycle, and its expression has also been observed in various types of cancer. Further research is needed to fully understand the function of LINC01881 and its potential as a drug target and biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 1881

The "LINC01881 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01881 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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