LINC01943: A Long Intergenic Non-Protein-Coding RNA as a Drug Target and Biomarker

Target Name: LINC01943

NCBI ID: G101928173

LINC01943

Other Name(s): long intergenic non-protein coding RNA 1943 | Long intergenic non-protein coding RNA 1943

LINC01943: A Long Intergenic Non-Protein-Coding RNA as a Drug Target and Biomarker

LINC01943 is a long non-coding RNA (lncRNA) that has been identified in various studies as having important functional roles in various cellular processes. Its unique feature is its ability to interact with proteins, both in the intracellular and extracellular environments, which has led to its potential as a drug target or biomarker. In this article, we will explore the biology and potential applications of LINC01943 as a drug target and biomarker.

Biography of LINC01943

LINC01943 is a transcribed RNA molecule that falls within the long non-coding RNA (lncRNA) category. It was first identified in the ENCODE (Encyclopedia of DNA Elements) database and has a unique 5'-end exon that starts at position 228 and a 3'-end exon that starts at position 408. LINC01943 is made up of 1,252 amino acids and has a calculated molecular mass of 19.8 kDa.

LINC01943 is expressed in various tissues and cells, including human brain, heart, and liver. It is highly expressed in the brain, with a particularly high expression level in the prefrontal cortex. LINC01943 is also expressed in other tissues, including heart and liver, and has been shown to be involved in various cellular processes, including cell adhesion, migration, and signaling pathways.

Potential Applications as a Drug Target

The unique feature of LINC01943 is its ability to interact with proteins, both in the intracellular and extracellular environments. This interaction suggests that LINC01943 could be a potential drug target. Several studies have shown that LINC01943 can interact with various proteins, including the protein known as FAK (focal adhesion kinase).

FAK is a transmembrane protein that is involved in various cellular processes, including cell adhesion, migration, and signaling pathways. It has been shown to play a role in various diseases, including cancer, neurodegenerative diseases, and developmental disorders. LINC01943 has been shown to interact with FAK and can modulate its activity.

In addition to its interaction with FAK, LINC01943 has also been shown to interact with several other proteins, including the protein known as PDGF-?? (pluripotent stem cell factor beta). PDGF-?? is a transmembrane protein that is involved in various cellular processes, including stem cell maintenance and proliferation. LINC01943 has been shown to interact with PDGF-?? and can modulate its activity.

Potential Applications as a Biomarker

LINC01943 has also been shown to have potential as a biomarker for various diseases. Its unique expression pattern and interaction with other proteins make it an attractive candidate for diagnostic and therapeutic applications.

One potential application of LINC01943 as a biomarker is its ability to be downregulated in various diseases, such as cancer and neurodegenerative diseases. This downregulation can be used as a biomarker to track disease progression and the effectiveness of various treatments.

Another potential application of LINC01943 as a biomarker is its ability to be regulated by various factors, including drugs. This regulation can be used to track the efficacy of drugs and their potential off-target effects.

Conclusion

In conclusion, LINC01943 is a long non-coding RNA that has unique characteristics, including its ability to interact with proteins both in the intracellular and extracellular environments. Its expression pattern and interaction with other proteins make it an attractive candidate for drug targeting and biomarker applications. Further studies are needed to fully understand the biology and potential applications of LINC01943.

Protein Name: Long Intergenic Non-protein Coding RNA 1943

The "LINC01943 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01943 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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