LOC101928007: A Protein Implicated in Cancer and PD-L1 Interaction

LOC101928007: A Protein Implicated in Cancer and PD-L1 Interaction

LOC101928007 (LOC101928007 variant X2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the T-cell antigen 6 (TCA6) family, which is a group of cytokines that play a critical role in the immune system.

LOC101928007 variant X2 is characterized by a single amino acid substitution at its C-terminus, which results in a change from Asp to Asn. This substitution has implications for the structure and function of the protein.

The C-terminus of LOC101928007 is involved in the formation of a unique structural domain that is conserved across different species. This domain is composed of a series of parallel beta-strands that are coiled together in a specific order. This order is important for the protein's stability and function, as changes in the arrangement of these beta-strands can disrupt the protein's stability and disrupt its ability to interact with other proteins.

The substitution of Asp for Asn at the C-terminus of LOC101928007 has resulted in a protein that is more than 10% larger than the wild-type protein. This size increase may have implications for the protein's stability or function, although more research is needed to determine exactly how this substitution affects the protein.

LOC101928007 variant X2 has been shown to interact with several different proteins, including the protein PD-L1. This interaction suggests that the protein may play a role in regulating immune responses and may be a potential drug target.

Additionally, LOC101928007 variant X2 has been shown to promote the development of cancer in animal models. This suggests that the protein may be a potential biomarker for cancer and may be a target for cancer therapies.

In conclusion, LOC101928007 (LOC101928007 variant X2) is a protein that is characterized by a single amino acid substitution at its C-terminus. This substitution has implications for the protein's structure and function, and has been shown to interact with several different proteins, including PD-L1. Additionally, LOC101928007 variant X2 has been shown to promote the development of cancer in animal models, making it a potential biomarker for cancer and a target for cancer therapies. Further research is needed to fully understand the role of LOC101928007 variant X2 in the immune system and its potential as a drug target.

Protein Name: Uncharacterized LOC101928007

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