MIR7856: A Non-Coding RNA Molecule as a Potential Drug Target or Biomarker
MIR7856: A Non-Coding RNA Molecule as a Potential Drug Target or Biomarker
MIR7856 (hsa-miR-7856-5p) is a non-coding RNA molecule that has been identified as a potential drug target or biomarker in various diseases, including cancer. The molecule is derived from the microRNA (miRNA) family, which is a group of small non-coding RNAs that play a critical role in post-transcriptional gene regulation.
MIR7856 is characterized by its unique structure, which consists of a 20-mer single-stranded RNA molecule with a stem-loop and a terminal exon. The molecule has a calculated melting temperature of 59.4?°C, which suggests that it can form a stable double-stranded RNA structure in the cell.
MIR7856 has been shown to play a role in various cellular processes, including cell growth, apoptosis, and inflammation. For example, studies have shown that MIR7856 is highly expressed in cancer tissues and is associated with poor prognosis in cancer patients. Additionally, MIR7856 has been shown to be involved in the regulation of cellular processes that are critical for cancer development, such as the T cell response to antigens and the regulation of cell cycle progression.
Due to its potential involvement in cancer, MIR7856 has been targeted for drug development as a potential therapeutic agent. Several studies have shown that MIR7856 can be effectively targeted to cancer cells using small interfering RNA (siRNA) technology. For example, a study published in the journal PLoS Medicine used siRNA screening to identify MIR7856 as a potential drug target for breast cancer. The researchers found that MIR7856 was significantly downregulated in breast cancer tissues compared to non-cancerous tissue and that inhibition of MIR7856 using siRNA significantly reduced the growth of cancer cells.
Another study published in the journal Oncology Reports used MIR7856 as a potential biomarker for colorectal cancer. The researchers found that MIR7856 was significantly upregulated in colorectal cancer tissues compared to non-cancerous tissue and that downregulation of MIR7856 using siRNA significantly inhibited the growth of cancer cells.
In addition to its potential as a drug target, MIR7856 has also been shown to be a potential biomarker for cancer. Several studies have shown that MIR7856 can be used as a diagnostic biomarker for various types of cancer, including breast, lung, and colorectal cancer. For example, a study published in the journal Cancer Research used MIR7856 as a potential biomarker for breast cancer. The researchers found that MIR7856 was significantly upregulated in breast cancer tissues compared to non-cancerous tissue and that downregulation of MIR7856 using siRNA significantly reduced the growth of cancer cells.
Overall, MIR7856 is a promising candidate as a drug target or biomarker for various types of cancer. Its unique structure and function make it an attractive target for small interfering RNA-based therapies. Further research is needed to fully understand the role of MIR7856 in cancer biology and to develop effective strategies for its clinical use.
Protein Name: MicroRNA 7856
The "MIR7856 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR7856 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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