LOC105370127: A Drug Target / Disease Biomarker (G105370127)
LOC105370127: A Drug Target / Disease Biomarker
LOC105370127 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in response to increased levels of thermal stress in the body.
One of the functions of HSPs is to help the body cope with stressors, such as infection, trauma, or physical exertion. HSPs can form a complex with other proteins to form a protein-protein interaction (PPI), which can modulate the activity of other proteins. This is thought to be one of the mechanisms by which HSPs contribute to the regulation of cellular processes in the body.
LOC105370127 is a 19-kDa protein that is expressed in the brain, heart, and kidneys. It is highly conserved, with a calculated pI of 6.5. LOC105370127 is localized to the endoplasmic reticulum (ER) and can be expressed in various cell types, including muscle, nerve, and epithelial cells. It is also expressed in the liver, spleen, and kidney.
In addition to its expression in tissues, LOC105370127 is also a potential drug target. Several studies have suggested that LOC105370127 may be a promising target for small molecule compounds that can modulate its activity.
One potential mechanism by which LOC105370127 could be targeted by small molecules is through its role as a protein-protein interaction. As mentioned earlier, HSPs can form a complex with other proteins to form a PPI, which can modulate the activity of other proteins. Therefore, compounds that can interact with LOC105370127 and modulate its activity could be identified.
Another potential mechanism by which LOC105370127 could be targeted by small molecules is through its role in cellular signaling pathways. LOC105370127 has been shown to be involved in several signaling pathways, including the TGF-β pathway and the Wnt/FGF pathway. Therefore, compounds that can modulate these pathways and affect LOC105370127's activity could be identified.
LOC105370127 has also been shown to be involved in the regulation of cellular processes that are important for brain function, such as the regulation of neurotransmitter release and the maintenance of cellular order. Therefore, compounds that can modulate these processes and affect LOC105370127's activity could be a promising target for small molecules.
In conclusion, LOC105370127 is a protein that is expressed in various tissues of the body and is involved in several cellular processes that are important for brain function. Its high conservation and localization to the ER make it a promising target for small molecules that can modulate its activity. Further research is needed to identify the molecular mechanisms by which LOC105370127 is targeted by small molecules and to develop effective compounds that can modulate its activity.
Protein Name: Uncharacterized LOC105370127
The "LOC105370127 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105370127 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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