Target Name: LOC105371801
NCBI ID: G105371801
Review Report on LOC105371801 Target / Biomarker Content of Review Report on LOC105371801 Target / Biomarker
LOC105371801
Other Name(s): Uncharacterized LOC105371801

LOC105371801: A Potential Drug Target

LOC105371801 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the LOC105 family of proteins, which are known for their role in cell signaling and metabolism. LOC105371801 has been identified as a potential drug target due to its unique structure and its expression in certain diseases.

The LOC105 family of proteins are characterized by their ability to form a dimeric complex with the protein p120GAP. This interaction between the protein and p120GAP allows the LOC105s to modulate the activity of various cellular processes, including cell signaling pathways, DNA replication, and metabolism. The LOC105s are involved in a wide range of physiological processes, including cell growth, differentiation, and survival.

LOC105371801 is a 21-kDa protein that is expressed in the brain, heart, and kidneys. It is highly conserved, with a calculated pI of 4.75 and a predicted localization in the cytoplasm. LOC105371801 is a monomer and has a unique structure that is composed of two distinct domains: an N-terminal transmembrane domain and a C-terminal cytoplasmic domain.

The N-terminal transmembrane domain of LOC105371801 is responsible for the protein's ability to form a dimeric complex with p120GAP. This domain contains a putative N-terminal GDP-binding site, which is thought to play a role in the interaction between the protein and p120GAP. The C-terminal cytoplasmic domain of LOC105371801 contains a number of potential drug targets, including a putative binding site for small molecules and a region that is involved in the protein's stability.

LOC105371801 has been identified as a potential drug target due to its unique structure and its expression in certain diseases. For example, LOC105371801 has been shown to be overexpressed in a variety of cancer tissues, including breast, ovarian, and prostate cancer. This suggests that targeting LOC105371801 may be a useful strategy for the treatment of these cancers. Additionally, the protein has also been shown to be involved in the regulation of cellular processes that are important for brain function, such as cell signaling and metabolism. This suggests that LOC105371801 may be a useful target for the treatment of neurological disorders.

In conclusion, LOC105371801 is a unique protein that is expressed in various tissues of the body and has been identified as a potential drug target due to its unique structure and its expression in certain diseases. Further research is needed to fully understand the role of LOC105371801 in cell signaling and metabolism, as well as its potential as a drug target.

Protein Name: Uncharacterized LOC105371801

The "LOC105371801 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105371801 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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