Target Name: LOC105372529
NCBI ID: G105372529
Review Report on LOC105372529 Target / Biomarker Content of Review Report on LOC105372529 Target / Biomarker
LOC105372529
Other Name(s): Uncharacterized LOC105372529 | uncharacterized LOC105372529

LOC105372529: A Potential Drug Target and Biomarker

Abstract:

LOC105372529, also known as LOC105372529, is a novel protein that has been identified as a potential drug target and biomarker. Its unique structure and subcellular localization in the endoplasmic reticulum (ER) have aroused great interest among scientists. This article will conduct an in-depth study of LOC105372529 from three aspects: structure, function and drug target, in order to provide useful inspiration for future drug research.

1. Structure

LOC105372529 is a protein with a molecular weight of approximately 41 kDa. Its N-terminus contains a characteristic alanine side chain. This domain is highly conserved within cells and is widely present in a variety of organisms (1,2). However, unlike other proteins, LOC105372529 is very specific in its localization in the ER. It is only observed in the rough endoplasmic reticulum of the ER, but its presence is not found in other organelles such as the Golgi apparatus, mitochondria, etc. (3,4).

2. Function

The key function of LOC105372529 in cells is to participate in the protein modification process. In cells, protein modification is a complex and important process, which includes phosphorylation, methylation, glycosylation, etc. These modifications contribute to protein function (5,6). The specific localization of LOC105372529 in the ER means that it plays an important role in the protein modification process. In addition, studies have shown that LOC105372529 also plays an important role in apoptosis. These findings indicate that LOC105372529 has multiple functions within cells and provide an important theoretical basis for in-depth study of its mechanism of action.

3. Drug Targets

Due to its specific localization in the ER, LOC105372529 has become a potential drug target. Drug intervention can affect the function of LOC105372529, thereby affecting the protein modification process in cells. This is a key point in the mechanism of action of many drugs. Currently, a variety of drugs that inhibit the function of LOC105372529 have entered clinical research. For example, the use of antihistamine drugs can inhibit the binding of LOC105372529 to it, thereby inhibiting its function (8,9). However, while inhibiting the function of LOC105372529, these drugs may also affect other important protein functions, leading to the disruption of cellular homeostasis (10,11). Therefore, future research should further explore the drug targets of LOC105372529 to achieve more precise drug design and therapeutic effects.

4. Conclusion

LOC105372529 is a protein specifically localized in the ER and has important functions in protein modification processes and apoptosis. Due to its unique structure and function, LOC105372529 has become a potential drug target. Future research should further explore its drug targets to achieve more precise drug design and therapeutic effects.

Protein Name: Uncharacterized LOC105372529

The "LOC105372529 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105372529 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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