LOC105374362: A Potential Drug Target and Biomarker (G105374362)
LOC105374362: A Potential Drug Target and Biomarker
Abstract:
LOC105374362, also known as X3, is a non-coding RNA molecule located within the gene cluster of the LOC105374362 gene. It has been identified as a potential drug target and biomarker due to its unique structure, stability, and expression pattern in various organisms. This article will provide an overview of LOC105374362, including its function, potential drug targets, and its potential as a biomarker for various diseases.
Introduction:
The LOC105374362 gene is located within the human genomic imprinting region, which is known for its ability to regulate gene expression and play a role in various cellular processes. The gene has been shown to encode for a non-coding RNA molecule that has been named LOC105374362 (LOC105374362) due to its unique structure, stability, and expression pattern.
Location and Expression:
LOC105374362 is located within the LOC105374362 gene, which encodes for a protein with three distinct isoforms: Isolet1, Isolet2, and Isolet3. The gene is located on chromosome 6p21.3, and its expression pattern varies among individuals and organisms. LOC105374362 has been shown to be highly expressed in various tissues, including brain, heart, liver, and muscle. It is also shown to be expressed in various cell types, including stem cells, progenitor cells, and differentiated cells.
Structure and stability:
LOC105374362 is a non-coding RNA molecule that has a unique structure that allows it to interact with various proteins and factors in the cell. It is composed of 194 amino acid residues and has a calculated molecular mass of 23.9 kDa. The molecule has a characteristic stem-loop structure that is composed of a central alpha-helices and a 5' and 3' terminal region of beta-helices. This structure allows the molecule to interact with various RNA factors and protein partners.
LOC105374362 has been shown to have various stability properties, including stability in various cellular compartments and in cell-free solution. Studies have shown that LOC105374362 has a stable expression pattern in various organisms, including human, mouse, and rat. It has also been shown to have a stable structure in various cell types, including stem cells, progenitor cells, and differentiated cells.
Potential Drug Target:
LOC105374362 has been identified as a potential drug target due to its unique structure and stability. Its beta-helices and stem-loop structure make it a potential target for small molecules, antibodies, or other therapeutic agents that can interact with the molecule and modulate its stability or function.
In addition, LOC105374362 has been shown to play a role in various cellular processes, including cell adhesion, migration, and transcriptional regulation. Its expression has been shown to be involved in the regulation of various gene expression pathways, including the Wnt signaling pathway, the NF-kappa pathway, and the NF-kappa-B pathway.
Biomarker Potential:
LOC105374362 has potential as a biomarker for various diseases due to its unique expression pattern and stability. Its expression has been shown to be involved in the regulation of various cellular processes, including cancer, neurodegenerative diseases, and cardiovascular diseases.
In addition, LOC105374362 has been shown to have a stable expression pattern in various disease states, which could make it a potential biomarker for disease diagnosis or
Protein Name: Uncharacterized LOC105374362, Transcript Variant X3
The "LOC105374362 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105374362 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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