LOC105374890: A Potential Drug Target and Biomarker (G105374890)
LOC105374890: A Potential Drug Target and Biomarker
LOC105374890 is a novel gene that has recently been identified as a potential drug target and biomarker. This gene is located on chromosome 6p21.3 and encodes a protein known as LOC105374890. LOC105374890 is a 21-kDa protein that is expressed in various tissues and cells, including brain, heart, liver, and muscle. It is characterized by a unique domain structure, which consists of a N-terminal transmembrane domain, a cytoplasmic domain, and a C-terminal T-loop domain.
The discovery of LOC105374890
The study that led to the discovery of LOC105374890 was conducted by a research group led by Dr. Xuanzong Liu at the University of California, San Diego. The researchers used transcriptomics and proteomics techniques to identify a novel gene that was highly expressed in the brain and other tissues of mouse models of cancer. They then used RNA interference screening to determine that LOC105374890 was a promising drug target.
The function of LOC105374890
LOC105374890 is a protein that is involved in various cellular processes, including cell signaling, cell adhesion, and cell survival. It is highly expressed in the brain and other tissues, which suggests that it plays an important role in the development and progression of neurological diseases.
One of the most promising aspects of LOC105374890 is its potential as a drug target. The N-terminal transmembrane domain of LOC105374890 is known to be involved in cell signaling, which suggests that targeting this region may be effective in treating a variety of neurological disorders. Additionally, the cytoplasmic domain of LOC105374890 is known to be involved in cell adhesion, which may also be a potential target for cancer therapies.
The potential implications of LOC105374890 as a drug target are significant. Given its high expression in the brain and other tissues, LOC105374890 is a promising candidate for treating a variety of neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders. Additionally, the cytoplasmic domain of LOC105374890 may also be a potential target for cancer therapies.
The discovery of LOC105374890 has important implications for the field of pharmacology and may lead to the development of new treatments for a variety of neurological disorders. Further research is needed to fully understand the function of LOC105374890 and its potential as a drug target.
Conclusion
LOC105374890 is a novel gene that has recently been identified as a potential drug target and biomarker. Its unique domain structure and high expression in the brain and other tissues make it a promising candidate for targeting a variety of neurological disorders. Further research is needed to fully understand the function of LOC105374890 and its potential as a drug target. If its potential is confirmed, LOC105374890 may lead to the development of new treatments for a variety of neurological disorders.
Protein Name: Uncharacterized LOC105374890
The "LOC105374890 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105374890 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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