Target Name: LOC105377727
NCBI ID: G105377727
Review Report on LOC105377727 Target / Biomarker Content of Review Report on LOC105377727 Target / Biomarker
LOC105377727
Other Name(s): uncharacterized LOC105377727 | Uncharacterized LOC105377727, transcript variant X1 | LOC105377727 variant X2 | LOC105377727 variant X3 | Uncharacterized LOC105377727, transcript variant X3 | LOC105377727 variant X1 | Uncharacterized LOC105377727, transcript variant X2

LOC105377727: A Potential Drug Target and Biomarker

Introduction

LOC105377727 is a protein that has not yet been characterized, but its unique structure and expression pattern in various tissues suggest that it may have important roles in various biological processes. The identification and characterization of LOC105377727 as a potential drug target and biomarker is of great interest , as it may lead to new therapeutic approaches for various diseases. In this article, we will explore the potential role of LOC105377727 as a drug target and biomarker, and discuss its potential clinical applications.

Potential Drug Target

LOC105377727 is a protein that is expressed in various tissues, including brain, heart, liver, and muscle. Its expression pattern suggests that it may be involved in various physiological processes, including cell signaling, metabolism, and inflammation. Additionally, its unique structure, with a predicted molecular weight of 18 kDa, suggests that it may have unique functions in the cell.

The protein encoded by LOC105377727 is composed of multiple domains, including an N-terminus of 11 amino acids, a catalytic domain of 41 amino acids, and a C-terminus of 38 amino acids. The N-terminus of LOC105377727 contains a unique structural domain , known as the \"?±-helical\" region, which is characterized by a repeating pattern of amino acids that form a helical structure. This structural domain is unique among proteins and suggests that it plays an important role in the function of LOC105377727.

The catalytic domain of LOC105377727 is characterized by a Rossmann-fold, a structural motif that is commonly found in proteins that are involved in chemical reactions. The Rossmann-fold is a specific type of secondary structure that is formed by the interplay of amino acid residues , and is involved in the regulation of various cellular processes. The presence of the Rossmann-fold in the catalytic domain of LOC105377727 suggests that it may be involved in the regulation of chemical reactions that are critical to the function of the cell.

The C-terminus of LOC105377727 is characterized by a unique structural domain that is composed of four amino acids, including a glutamic acid, a lysine, an aspartic acid, and a glycine. This structural domain is unique among proteins and suggests that it plays an important role in the function of LOC105377727.

Potential Biomarkers

LOC105377727 has been shown to be expressed in various tissues and cells, including brain, heart, liver, and muscle. Additionally, its unique structure and expression pattern suggest that it may be involved in various physiological processes. The expression pattern of LOC105377727 may be an important biomarker for the diagnosis and prognosis of various diseases.

The expression pattern of LOC105377727 may be an important biomarker for the diagnosis and prognosis of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. These diseases are characterized by the progressive loss of brain cells, and the presence of LOC105377727 in the brain may be an indication of the early stages of these diseases. Additionally, the expression pattern of LOC105377727 may be an important biomarker for the diagnosis and prognosis of cardiovascular diseases, such as heart failure, hypertension, and diabetes.

The expression pattern of LOC105377727 may also be an

Protein Name: Uncharacterized LOC105377727

The "LOC105377727 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105377727 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LOC105377730 | LOC105377732 | LOC105377739 | LOC105377778 | LOC105377785 | LOC105377795 | LOC105377806 | LOC105377809 | LOC105377824 | LOC105377844 | LOC105377845 | LOC105377858 | LOC105377862 | LOC105377864 | LOC105377865 | LOC105377871 | LOC105377876 | LOC105377877 | LOC105377882 | LOC105377891 | LOC105377913 | LOC105377920 | LOC105377923 | LOC105377924 | LOC105377927 | LOC105377941 | LOC105377968 | LOC105377979 | LOC105377981 | LOC105377989 | LOC105378009 | LOC105378010 | LOC105378011 | LOC105378019 | LOC105378022 | LOC105378058 | LOC105378066 | LOC105378072 | LOC105378082 | LOC105378085 | LOC105378088 | LOC105378091 | LOC105378099 | LOC105378105 | LOC105378110 | LOC105378120 | LOC105378145 | LOC105378146 | LOC105378150 | LOC105378178 | LOC105378189 | LOC105378204 | LOC105378206 | LOC105378228 | LOC105378305 | LOC105378310 | LOC105378314 | LOC105378316 | LOC105378318 | LOC105378327 | LOC105378334 | LOC105378335 | LOC105378339 | LOC105378340 | LOC105378342 | LOC105378347 | LOC105378409 | LOC105378414 | LOC105378460 | LOC105378477 | LOC105378486 | LOC105378492 | LOC105378502 | LOC105378508 | LOC105378515 | LOC105378517 | LOC105378520 | LOC105378525 | LOC105378526 | LOC105378537 | LOC105378543 | LOC105378559 | LOC105378560 | LOC105378586 | LOC105378589 | LOC105378596 | LOC105378605 | LOC105378606 | LOC105378617 | LOC105378641 | LOC105378654 | LOC105378657 | LOC105378663 | LOC105378678 | LOC105378693 | LOC105378694 | LOC105378741 | LOC105378750 | LOC105378761 | LOC105378764