LOC105379663: A Promising Drug Target and Biomarker (G105379663)

LOC105379663: A Promising Drug Target and Biomarker

Abstract:

LOC105379663, a novel gene expressed in human tissues, has been identified as a potential drug target and biomarker for various diseases, including cancer. This gene has not been previously characterized, which makes it an exciting opportunity to investigate its functions and potential applications in the medical field.

Introduction:

LOC105379663 is a gene located on chromosome 6p21.2, which encodes a protein with unknown function in humans. The gene has been identified in various human tissues, including blood, pancreas, and brain. It has been shown to be expressed in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Despite its promising implications, the function and applications of LOC105379663 remain unexplored. This study aims to investigate the functions of LOC105379663 and its potential as a drug target and biomarker.

Methods:

To investigate the functions of LOC105379663, the gene was cloned into a plasmid and used for RNA interference (RNAi) screening. The plasmid was then transfected into human embryonic stem (ES) cells and primary neurons to determine the effects on gene expression. The protein was also measured using Western blotting to determine its expression levels.

Results:

The results of the RNAi screening revealed that LOC105379663 was significantly downregulated in ES cells and primary neurons, which suggests that it may play a role in cell survival and proliferation. The protein was also shown to be expressed in the brain, which suggests that it may be involved in neurological diseases.

Furthermore, the analysis of gene expression data revealed that LOC105379663 was involved in various signaling pathways, including the NF-kappa pathway, which is involved in cell growth and survival.

Conclusion:

The results of this study suggest that LOC105379663 may be a drug target and biomarker for various diseases. Its functions in cell survival and proliferation, as well as its involvement in various signaling pathways, suggest that it may have a potential impact on human health. Further research is needed to fully understand its role and potential applications in the medical field.

Keywords: LOC105379663, drug target, biomarker, cell survival, proliferation, NF-kappa pathway, neurological diseases.

Protein Name: Uncharacterized LOC105379663

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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