Exploring the Potential Drug Target and Biomarker, RN7SKP252, for Small Nuclear Pseudogenes

Target Name: RN7SKP252

NCBI ID: G106479207

RN7SKP252

Other Name(s): RNA, 7SK small nuclear pseudogene 252 | RN7SK pseudogene 252

Exploring the Potential Drug Target and Biomarker, RN7SKP252, for Small Nuclear Pseudogenes

Small nuclear pseudogenes (SNPs) are genomic regions that have been preserved in the DNA but have lost their functional relevance due to gene repression. Despite the fact that SNPs are highly conserved, they have been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The identification and characterization of potential drug targets and biomarkers for SNPs are crucial for the development of new therapeutic approaches. In this article, we will explore the potential drug target and biomarker, RN7SKP252, located on the 7SK small nuclear pseudogene 252.

RNA Structure and Expression

RNA structure and expression are critical factors in the function of SNPs. RN7SKP252 is a 23.8 kb RNA molecule with a single exon that is predominantly expressed in the brain and nervous tissue. It contains 19 exons, 18 of which are exons that encode the amino acids responsible for the protein structure and function. The exon starting at position 21 has a 5'-end that is 70 nt upstream of the start codon.

RNA levels and Expression Patterns

RNA levels of RN7SKP252 are highly variable, with peak expression levels achieved at different stages of the cell cycle, including G1, S, and G2. The RNA levels of RN7SKP252 have been shown to be regulated by various factors, including the expression of enzymes involved in RNA synthesis and processing, such as RNA polymerase II (RNA-pol), splicing factors, and microRNA (miRNA) interactors.

Function and Interaction with Other Genes

RN7SKP252 has been shown to interact with various other genes, including PRDM1, PRDM2, UBE2A, and USP9. PRDM1 and PRDM2 are known as microRNA-converting enzymes that regulate the expression of various genes, including RN7SKP252. UBE2A is a DNA damage repair enzyme that is involved in the repair of double-strand breaks, which can lead to the loss of RNA stability. USP9 is a protein that is involved in the regulation of DNA replication, which is a critical process for the maintenance of RNA stability.

Drug Target and Biomarker Potential

The potential drug target for RN7SKP252 is its role in the regulation of RNA stability, which is a crucial process for the survival of RNA molecules in the cell. Several studies have shown that RN7SKP252 is involved in the regulation of various RNA stability factors, including the stability of mRNAs in the cytoplasm and the stability of rRNAs in the endoplasmic reticulum.

In addition, RN7SKP252 has also been shown to play a role in the regulation of gene expression and has been shown to be involved in the regulation of various cellular processes, including cell growth, apoptosis, and cell cycle progression.

Biomarker Potential

The potential use of RN7SKP252 as a biomarker for various diseases is an attractive prospect due to its potential utility as a drug target. Several studies have shown that RN7SKP252 is involved in the regulation of various cellular processes and its levels have been shown to be regulated by various factors, including the expression of enzymes involved in RNA synthesis and processing.

RNA-based biomarkers have the potential to be non-invasive, culture-independent, and have the potential to detect changes in gene expression levels in a

Protein Name: RN7SK Pseudogene 252

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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