Unlocking The Potential of IGHV3-15 (G28448)

Target Name: IGHV3-15

NCBI ID: G28448

IGHV3-15

Other Name(s): immunoglobulin heavy variable 3-15 | Immunoglobulin heavy variable 3-15 | IGHV315 | VH

Unlocking The Potential of IGHV3-15

IGHV3-15, also known as immunoglobulin heavy variable 3-15 (IgHV3-15), is a unique protein that is expressed in the human body. It is a type of immunoglobulin, which is a protein that is produced by the immune system to help fight off infections and other harmful substances. There are several different types of immunoglobulins, each with a different number of constant and variable regions. IGHV3-15 is one of the proteins that contains a variable region.

The variable region of IGHV3-15 is made up of 15 constant and 6 variable regions. The constant regions are the same for all different types of immunoglobulins, while the variable regions are unique to each protein. The variable regions of IGHV3-15 contain the majority of the protein's unique features and are what give it its unique identity.

One of the key functions of IGHV3-15 is that it helps to stimulate the immune system. When the immune system is triggered, it sends out a response to help fight off the infection or other harmful substance. This response involves the production of antibodies, which are proteins that are specifically designed to recognize and neutralize the infection or substance. IGHV3-15 is involved in this process by helping to stimulate the production of antibodies.

Another important function of IGHV3-15 is that it helps to regulate the immune system. The immune system is a complex system that is responsible for protecting the body against infections and other harmful substances. However, if the immune system becomes too active or starts to attack the body's own cells, this can cause a range of problems. IGHV3-15 helps to regulate the immune system by helping to prevent this from happening.

IGHV3-15 is also a potential drug target. Researchers are studying the potential uses of IGHV3-15 as a treatment for a variety of different conditions. For example, some studies have suggested that IGHV3-15 may be a useful treatment for cancer, as it has been shown to have anti-tumor effects in cell cultures. Other studies have suggested that IGHV3-15 may be a potential treatment for autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

Overall, IGHV3-15 is a unique and important protein that plays a vital role in the immune system. Its unique structure and functions make it an attractive target for research and potential treatment. Further studies are needed to fully understand the potential uses of IGHV3-15 and to determine just how this protein can help to improve the health and well-being of people.

Protein Name: Immunoglobulin Heavy Variable 3-15

Functions: V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170)

The "IGHV3-15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IGHV3-15 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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