LINC01591: A Long Intergenic Non-Protein Coding RNA (G286094)

Target Name: LINC01591

NCBI ID: G286094

LINC01591

Other Name(s): long intergenic non-protein coding RNA 1591 | Long intergenic non-protein coding RNA 1591, transcript variant 1

LINC01591: A Long Intergenic Non-Protein Coding RNA

Introduction

LINC01591 is a long non-coding RNA (lncRNA) that has been identified in various organisms, including humans. It is characterized by its unique properties of being a long intergenic RNA and not containing any protein coding sequences. LINC01591 has been found to be involved in various cellular processes, including cell signaling, RNA processing, and regulation of gene expression. Its function and potential as a drug target or biomarker make it an attractive target for further research.

Structure and Expression

LINC01591 is a 21.9 kilobase (kb) RNA molecule with a unique feature of having a stem-loop structure at its 5' end. It has a calculated RNA secondary structure of 6.8 entropy, which is higher than the typical value of 4 entropy for proteins . This higher entropy value suggests that LINC01591 may have a more stable structure than typical non-protein coding RNAs (ncRNAs), which could be important for its functions.

LINC01591 is expressed in various cell types, including brain, heart, and liver, and has been shown to be expressed at different levels in different cell types. It is also a good candidate for a potential drug target due to its expression in multiple tissues and its unique properties.

Function and Potential as a Drug Target

LINC01591 has been shown to be involved in various cellular processes, including cell signaling, RNA processing, and regulation of gene expression. Its function in cell signaling is related to the T-cell receptor (TCR) signaling pathway, which is a critical pathway involved in immune response and regulation of cell growth.

LINC01591 has been shown to be a negative regulator of the T-cell receptor (TCR) gene, which encodes the surface antigens that recognize foreign particles in the immune system. LINC01591 has been shown to prevent the degradation of the T-cell receptor (TCR) ) gene by using a unique mechanism of RNA-protein interaction, which involves the formation of a complex between LINC01591 and the T-cell receptor (TCR) protein.

LINC01591 has also been shown to be involved in the regulation of gene expression by RNA polymerase (RNA-P) in various cell types. RNA-P is a protein that uses RNA as a template to synthesize a new RNA molecule. LINC01591 has been shown to prevent the activity of RNA-P, which is a potential drug target for treating various diseases.

Potential as a Biomarker

LINC01591 has also been shown to be involved in the regulation of cell death, which is an important aspect of disease development. in the regulation of cell death by using a unique mechanism of RNA-protein interaction, which involves the formation of a complex between LINC01591 and the BCL-2 protein.

Conclusion

LINC01591 is a long non-coding RNA (ncRNA) that has unique properties of being a long intergenic RNA and not containing any protein coding sequences. It has been shown to be involved in various cellular processes, including cell signaling, RNA processing, and regulation of gene expression. Its function and potential as a drug target or biomarker make it an attractive target for further research. Further studies are needed to determine the exact function of LINC01591 and its potential as a drug or biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 1591

The "LINC01591 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01591 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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