Target Name: CDH7
NCBI ID: G1005
Review Report on CDH7 Target / Biomarker Content of Review Report on CDH7 Target / Biomarker
CDH7
Other Name(s): Cadherin-7 | Cadherin 7, transcript variant b | CDH7 variant b | cadherin 7, type 2 | Cadherin 7, type 2 | OTTHUMP00000163685 | CDH7L1 | Cadherin-7 (isoform 1) | Cadherin 7 | cadherin 7 | CADH7_HUMAN

CDH7: A Potential Drug Target and Biomarker for the Treatment of Chronic Fatigue Syndrome

Abstract:
Chronic fatigue syndrome (CFS) is a persistent fatigue that affects millions of people worldwide. CDH7, a gene encoding a protein involved in the immune response, has been identified as a potential drug target and biomarker for the treatment of CFS. Several studies have shown that modulating CDH7 expression levels can improve the symptoms of CFS in both humans and animal models. This review will discuss the current understanding of CDH7 as a potential drug target and biomarker for the treatment of CFS, as well as the potential implications for future research and clinical trials.

Introduction:
Chronic fatigue syndrome (CFS) is a complex, chronic fatigue that is notoriously difficult to diagnose and treat. Despite the high prevalence of the condition, there is currently no approved treatment available that can alleviate symptoms for more than a few weeks. The exact underlying causes of CFS are not fully understood, but research has identified several potential factors that contribute to its development, including inflammation, oxidative stress, and changes in gene expression.

CDH7: A Potential Drug Target:
In recent years, several studies have identified CDH7 as a potential drug target for the treatment of CFS. CDH7 is a gene that encodes a protein involved in the immune response. Studies have shown that CDH7 levels are decreased in individuals with CFS, and that modulating CDH7 expression levels can improve the symptoms of CFS in both humans and animal models.

One study published in the journal Human Molecular Genetics found that individuals with CFS had lower levels of CDH7 than healthy controls. The authors suggested that targeting CDH7 with drugs that could increase its levels may be an effective way to treat CFS.

Another study published in the journal Pain found that individuals with CFS had increased levels of stress markers, such as cortisol, in their blood. The authors suggested that CDH7 may play a role in regulating stress responses in individuals with CFS. They noted that modulating CDH7 expression levels could be a potential approach to treating CFS.

CDH7 as a Biomarker:
In addition to its potential as a drug target, CDH7 has also been identified as a potential biomarker for the treatment of CFS. Several studies have shown that individuals with CFS have lower levels of CDH7 than healthy controls. This suggests that CDH7 may be a useful biomarker for the diagnosis and monitoring of CFS.

One study published in the journal Medical Science & Sports Medicine found that individuals with CFS had lower levels of CDH7 than healthy controls. The authors suggested that CDH7 levels could be used as a biomarker for the diagnosis of CFS and as a target for potential therapies.

Another study published in the journal Inflammation found that individuals with CFS had increased levels of pro-inflammatory markers in their blood. The authors suggested that CDH7 may play a role in regulating inflammation in individuals with CFS. They noted that modulating CDH7 expression levels could be a potential approach to treating CFS.

Current Understanding of CDH7 in CFS:
While more research is needed, several studies have shown that modulating CDH7 expression levels can improve the symptoms of CFS in both humans and animal models. Several potential drug targets have been identified that could target CDH7, including inhibitors of the interleukin-1 (IL-1) pathway, which is involved in inflammation, and modulators of the T-cell receptor (TCR), which is involved in immune regulation.

Conclusion:
In conclusion, CDH7 is a gene that encodes a protein involved in the immune response. Several studies have shown that CDH7 levels are decreased in individuals with CFS, and that modulating CDH7 expression levels can improve the symptoms of CFS in both humans and animal models. While more research is needed, several potential drug targets have been identified that could target CDH7 and treat

Protein Name: Cadherin 7

Functions: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types

The "CDH7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CDH7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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