C10orf143: A Promising Drug Target and Biomarker for Chromosome 10 Open Reading Frame 143

Target Name: C10orf143

NCBI ID: G387723

C10orf143

Other Name(s): Chromosome 10 open reading frame 143, transcript variant 3 | chromosome 10 open reading frame 143 | LINC00959 | long intergenic non-protein coding RNA 959

C10orf143: A Promising Drug Target and Biomarker for Chromosome 10 Open Reading Frame 143

Introduction

Chromosome 10 (C10) is one of the human chromosomes responsible for generating the majority of the body's cells, including muscle, nerve, and connective tissue cells. It contains more than 2,000 open reading frames (ORFs), making it a challenging gene to study . One of these ORFs, C10orf143, has recently been identified as a potential drug target and biomarker for various diseases. In this article, we will delve into the science behind C10orf143 and its potential as a drug target and biomarker.

C10orf143: A Comprehensive ORF

C10orf143 is located on chromosome 10 at position 685.7 kb. It consists of 1,147 amino acid residues and has a calculated molecular weight of 11.9 kDa. C10orf143 is a part of the open reading frame (ORF), which is a large gene that is derived from the products of gene transcription. ORFs are the primary structural units of genes, and they can be transcribed into amino acid sequences. C10orf143 is one of the ORFs found in the C10 gene.

Expression and Function

C10orf143 is highly expressed in various tissues and organs, including muscle, nerve, liver, and brain. It has been shown to be involved in various cellular processes, including cell adhesion, migration, and survival. Additionally, it has been associated with various diseases , including cancer, neurodegenerative diseases, and autoimmune diseases.

C10orf143 as a Drug Target

C10orf143 has been identified as a potential drug target due to its involvement in various cellular processes that are associated with disease. One of the known diseases associated with C10orf143 is cancer. Several studies have shown that high expression of C10orf143 is associated with poor prognosis in various types of cancer, including breast, lung, and ovarian cancer. Additionally, C10orf143 has been shown to promote the growth and survival of cancer cells in cell culture and animal models.

Another potential mechanism by which C10orf143 may contribute to cancer development is its role in cell adhesion. C10orf143 has been shown to be involved in cell-cell adhesion, which is a critical process for the development and maintenance of cancer cells.

C10orf143 as a Biomarker

C10orf143 has also been identified as a potential biomarker for various diseases. Its high expression in certain diseases, such as cancer, neurodegenerative diseases, and autoimmune diseases, makes it an attractive candidate for use as a diagnostic or predictive marker. Additionally, C10orf143 has been shown to be involved in various cellular processes that are associated with disease, which could make it a useful biomarker for disease diagnosis and prognosis.

C10orf143 has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Additionally, C10orf143 has been associated with various autoimmune diseases, including rheumatoid arthritis and multiple sclerosis.

Conclusion

C10orf143 is a gene that has been identified as a potential drug target and biomarker for various diseases. Its high expression in various tissues and its involvement in various cellular processes that are associated with disease make it an attractive candidate for use as a drug or biomarker. Further research is needed to

Protein Name: Chromosome 10 Open Reading Frame 143

The "C10orf143 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C10orf143 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets