A Promising Protein: C11orf96 as a Drug Target and Biomarker (G387763)

Target Name: C11orf96

NCBI ID: G387763

C11orf96

A Promising Protein: C11orf96 as a Drug Target and Biomarker

C11orf96 is a protein that has been identified by researchers as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and various post-translational modifications (PTMs) make it an attractive target for the development of new therapeutic approaches. In this article, we will explore the science behind C11orf96 and its potential as a drug target and biomarker.

Structure and Function

C11orf96 is a 21-kDa protein that is expressed in various tissues and organs, including brain, heart, muscle, and organs. Its protein structure is characterized by a long amino acid sequence that is rich in charged and polar amino acids, as well as several potential N-glycosylation sites. C11orf96 also has several well-documented PTMs, including N-acetylation, N-glutamylation, and N-phosphorylation, which are known to play important roles in protein function and stability.

C11orf96 functions as a transcription factor that regulates various gene expression patterns in various organisms. Its N-phosphorylation state has been shown to play a role in promoting protein stability and to influence protein-protein interactions, while its N-acetylation state has been linked to protein stability and modulation of protein-DNA interactions. These functions make C11orf96 a potential regulator of various cellular processes, including cell growth, apoptosis, and inflammation.

As a drug target, C11orf96 has been identified for its role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its potential as a drug target is based on its unique structure, which allows it to interact with small molecules and other proteins with high affinity. Several studies have shown that C11orf96 can interact with various small molecules, including inhibitors of its N-phosphorylation and N-acetylation states. These interactions may influence the activity and stability of C11orf96, potentially leading to changes in cellular processes that can be targeted by small molecules.

In addition to its potential as a drug target, C11orf96 has also been identified as a potential biomarker for several diseases. Its expression and stability have been shown to be altered in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These changes in expression and stability may be associated with the development and progression of these diseases, making C11orf96 a potential biomarker for these conditions.

Methods and Findings

To investigate the potential of C11orf96 as a drug target and biomarker, several studies have been conducted. These studies have focused on the characterization of C11orf96's protein structure, its interactions with small molecules, and its expression and stability in various diseases.

One of the most significant findings of these studies is the identification of C11orf96's N-phosphorylation state as a potential drug target. Several studies have shown that C11orf96 can interact with inhibitors of its N-phosphorylation state, leading to changes in its activity and stability. These interactions may influence the activity and stability of C11orf96, potentially leading to changes in cellular processes that can be targeted by small molecules.

Another finding of these studies is the identification of C11orf96's N-acetylation state as a potential biomarker for several diseases. Several studies have shown that C11orf96 expression and stability have been altered in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These changes in expression and stability may be associated with the development and progression of these diseases, making C11orf96 a potential biomarker

Protein Name: Chromosome 11 Open Reading Frame 96

The "C11orf96 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C11orf96 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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