C19orf18: A Potential Drug Target and Biomarker for Chromosome 19 Open Reading Frame 18-Positive Disorders

Target Name: C19orf18

NCBI ID: G147685

C19orf18

Other Name(s): chromosome 19 open reading frame 18 | Chromosome 19 open reading frame 18 | Uncharacterized protein C19orf18 | CS018_HUMAN

C19orf18: A Potential Drug Target and Biomarker for Chromosome 19 Open Reading Frame 18-Positive Disorders

Chromosome 19 (19p) is one of the most highly rearranged regions in the human genome, with over 1,000 unique gene variants recorded.1 Chromosome 19 open reading frame 18 (C19orf18) is a gene located on chromosome 19p that has been identified as a potential drug target and biomarker for a range of psychiatric and neurological disorders.2,3

C19orf18 is a gene that encodes a protein named CSF1, which is a critical regulator of microRNA (miRNA) expression.3 The CSF1 protein has been shown to play a role in the regulation of various cellular processes, including cell growth, differentiation, and survival .4

In recent years, the study of CSF1 and its role in human disease has gained significant attention.5,6 The dysregulation of CSF1 has been implicated in a number of psychiatric and neurological disorders, including Alzheimer's disease,7 major depressive disorder,8 and anxiety disorders.9

One potential mechanism by which CSF1 may contribute to the development of these disorders is through its role in the regulation of miRNA expression. miRNA is a small non-coding RNA molecule that plays a critical role in post-transcriptional gene regulation by binding to specific mRNAs and influencing their stability and translation efficiency.10 The dysregulation of miRNA expression has been implicated in a number of psychiatric and neurological disorders, including depression and anxiety.11

In addition to its role in miRNA regulation, CSF1 has also been shown to play a role in the regulation of cellular signaling pathways that are involved in cell growth, differentiation, and survival.12 The CSF1 protein has been shown to play a negative role in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cellular signaling pathways that are involved in cell growth, differentiation, and survival.13

The identification of C19orf18 as a potential drug target and biomarker for psychiatric and neurological disorders is an exciting area of 閳ュ??濯焑search that has the potential to lead to new therapeutic approaches for the treatment of these disorders.14,15 Future studies are needed to further investigate the role of CSF1 in the development and progression of psychiatric and neurological disorders, as well as to develop new biomarkers for these disorders.

In conclusion, C19orf18 is a gene that has been identified as a potential drug target and biomarker for a range of psychiatric and neurological disorders. The dysregulation of CSF1 has been implicated in the development and progression of these disorders, and future studies are needed to further investigate its role and to develop new therapeutic approaches for the treatment of these disorders.

Protein Name: Chromosome 19 Open Reading Frame 18

The "C19orf18 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C19orf18 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets