LINC00997: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

Target Name: LINC00997

NCBI ID: G401321

LINC00997

Other Name(s): long intergenic non-protein coding RNA 997 | Long intergenic non-protein coding RNA 997

LINC00997: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

Introduction

LINC00997 is a long intergenic non-protein coding RNA (lncRNA) that has been identified in various organisms, including humans. It has a unique feature that consists of 1,212 exons, 10,922 upstream non-coding RNA (ncRNA), and 727 downstream non-coding RNA (ncRNA) exons. LINC00997 is coded using a non-coding RNA (ncRNA) synthase II (NcSNAP) gene, which leads to the production of a 229-nt RNA molecule. The unique feature of LINC00997 is its ability to interact with various proteins , which has led to its potential involvement as a drug target or biomarker.

Drug Target Potential

LINC00997 has been shown to interact with several proteins, including HDACs, p53, and NF-kappa-B signaling pathway components. It has been shown to play a role in various cellular processes, including cell growth, apoptosis, and inflammation. Therefore, LINC00997 has great potential as a drug target. The development of small molecules that can interact with LINC00997 and modulate its activity could be a promising strategy for the development of new pharmaceuticals.

Biomarker Potential

LINC00997 has also been shown to be involved in various biological processes, including cell cycle progression, apoptosis, and inflammation. Therefore, it has great potential as a biomarker. The expression level of LINC00997 can be used as a marker for various diseases, including cancer , neurodegenerative diseases, and autoimmune diseases. The regulation of LINC00997 expression levels can also be used as a target for therapeutic interventions.

Function and Interaction

The function of LINC00997 is not well understood, but its interaction with various proteins suggests that it plays a role in regulating protein expression and cell signaling pathways. LINC00997 has been shown to interact with HDACs, which are known to play a role in the regulation of gene expression and protein synthesis. LINC00997 has also been shown to interact with p53, which is a well-known tumor suppressor protein that plays a role in the regulation of apoptosis.

Additionally, LINC00997 has been shown to interact with various signaling pathways, including the NF-kappa-B signaling pathway. NF-kappa-B is a transcription factor that plays a role in the regulation of inflammation, immune, and cellular processes. The regulation of LINC00997 expression by the NF-kappa-B signaling pathway suggests that it may be involved in the regulation of these processes.

Conclusion

LINC00997 is a long intergenic non-protein coding RNA that has unique features, including its ability to interact with various proteins. Its function and interaction suggest that it has the potential as a drug target or biomarker. Further research is needed to fully understand the role of LINC00997 in various biological processes and to develop new therapeutic interventions based on its unique properties.

Protein Name: Long Intergenic Non-protein Coding RNA 997

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•   general information;
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•   the target screening and validation;
•   expression level;
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