LINC00976: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

Target Name: LINC00976

NCBI ID: G106144608

LINC00976

Other Name(s): Long intergenic non-protein coding RNA 976 | long intergenic non-protein coding RNA 976

LINC00976: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

LINC00976 is a long non-coding RNA (lncRNA) that has been identified in various organisms, including humans. It has a unique feature, which is its ability to interact with proteins and other biomolecules. This interaction makes LINC00976 an attractive candidate as a drug target or biomarker. In this article, we will explore the biology and potential applications of LINC00976.

Biogenesis and Expression

LINC00976 is a long non-coding RNA that has a length of approximately 2.5 kilobases (kb) and is located between exons 16 and 17 of the human X chromosome. It is expressed in various tissues and cells of the body, including the brain, heart, and gastrointestinal tract. LINC00976 is a transcribed RNA molecule that is involved in the regulation of gene expression.

Function and Interaction with Proteins

LINC00976 has been shown to interact with various proteins, including the protein encoded by the gene SLC30A8. SLC30A8 is a zinc transporter that is involved in the uptake and excretion of zinc ions in the body. Zinc ions are essential for various biological processes, including cell growth, inflammation, and immune response.

LINC00976 has been shown to play a role in the regulation of SLC30A8 expression by binding to its mRNA and preventing its degradation. This interaction between LINC00976 and SLC30A8 suggests that LINC00976 may be a potential drug target or biomarker associated with SLC30A8 function.

Expression and Therapeutic Potential

The potential therapeutic applications of LINC00976 are vast. As a drug target, LINC00976 could be used to treat a variety of diseases associated with the over-expression of SLC30A8. For example, LINC00976 could be used to treat cancer, as over-expression of SLC30A8 has been associated with increased cancer risk.

Another potential application of LINC00976 is as a biomarker for diagnosing diseases associated with SLC30A8 over-expression. For instance, LINC00976 could be used as a diagnostic biomarker for neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. These diseases are characterized by the progressive loss of brain cells and can be treated with neuroprotective agents that target SLC30A8 function.

Conclusion

LINC00976 is a long non-coding RNA that has unique features, including its ability to interact with proteins and other biomolecules. Its interaction with the protein encoded by the gene SLC30A8 suggests that LINC00976 may be a potential drug target or biomarker associated with SLC30A8 function. Further research is needed to determine the full potential of LINC00976 as a therapeutic agent.

Protein Name: Long Intergenic Non-protein Coding RNA 976

The "LINC00976 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC00976 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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