Target Name: MIR199B
NCBI ID: G406978
Review Report on MIR199B Target / Biomarker Content of Review Report on MIR199B Target / Biomarker
MIR199B
Other Name(s): hsa-miR-199b-3p | microRNA 199b | MicroRNA 199b | hsa-mir-199b | hsa-miR-199b-5p | MIRN199B | mir-199b

MIR199B: A Potential Drug Target and Biomarker

MIR199B (hsa-miR-199b-3p), a non-coding RNA molecule, has been identified as a potential drug target and biomarker in various diseases, including cancer. Its unique structure, expression pattern, and function as a negative regulator of the microRNA (miRNA) pathway make it an attractive target for researchers to investigate.

MIR199B is a microRNA that is expressed in various tissues and cells of the body. It is a part of the miRNA-199b family, which consists of 21 non-coding RNAs. The miRNA pathway is a critical regulator of gene expression, and miRNA particles are small enough to enter the cytoplasm and interact with mRNAs to either activate or repress their translation into protein.

MIR199B has been shown to play a negative role in the miRNA pathway. It can bind to the miR199a protein, which is a long sequence of a miRNA target, and prevent it from binding to the target mRNAs. This interaction between MIR199B and miR199a suggests that MIR199B may be a negative regulator of the miRNA pathway.

MIR199B has also been shown to be involved in various diseases, including cancer. For example, it has been shown to be downregulated in various types of cancer, such as breast cancer, lung cancer, and colon cancer. Additionally, it has been shown to be involved in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

MIR199B may also be a potential biomarker for some diseases. Its expression pattern has been shown to be regulated by various factors, including cancer status, treatment, and environmental factors. For example, it has been shown to be downregulated in cancer cells, and its expression level can be increased by anti-cancer drugs. Additionally, it has been shown to be regulated by factors such as tissue type, developmental stage, and gene expression.

MIR199B's unique structure and function make it an attractive target for drug research. Its small size and the fact that it is a non-coding RNA molecule make it relatively easy to modify and study. MIR199B's negative regulation of the miRNA pathway and its involvement in various diseases make it a promising target for new drugs. Further research is needed to fully understand the role of MIR199B in disease and to develop new treatments.

Protein Name: MicroRNA 199b

The "MIR199B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR199B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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