Discovery and Function of The MIR2052HG Gene (G441355)
Discovery and Function of The MIR2052HG Gene
The MIR2052HG gene is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. The MIR2052HG gene is located on chromosome 6p21.2 and encodes a protein known as MIR2052, which is a key regulator of microRNA (miRNA) expression. MIR2052 plays a crucial role in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation.
The discovery of the MIR2052HG gene
The MIR2052HG gene was first identified using bioinformatics analysis of transcriptomic data from the gene expression profile of human cancer cell lines. The MIR2052HG gene was found to be highly expressed in various human cancer tissues, including breast, ovarian, and prostate cancer.
Function and localization of the MIR2052 protein
The MIR2052 protein is a 21-kDa protein that is expressed in various tissues and cells. It is highly expressed in the liver, and it is also expressed in the hearts, kidneys, and intestines. The MIR2052 protein is localized to the endoplasmic reticulum (ER) and the nuclear envelope (NE). It is also associated with the endoplasmic reticulum protein (ERP) complex, which is a complex of proteins that play a role in the delivery of proteins to the ER.
The MIR2052 gene is involved in the regulation of miRNA expression
The MIR2052HG gene is involved in the regulation of miRNA (miRNA) expression, which is a small non-coding RNA molecule that plays a crucial role in post-transcriptional gene regulation. MiRNA expression is regulated by a complex of miRNA-binding proteins (miBPs) and factors that interact with the RNA-binding domain of the miRNA.
The MIR2052 protein is a miRNA target
The MIR2052HG gene is a known miRNA target, which means that it is targeted by miBPs that interact with the miRNA. The miRNA-binding proteins (miBPs) that interact with the MIR2052 protein include miR-18a, miR-202, and miR-205. These miBPs are involved in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation.
The MIR2052HG gene is also a potential biomarker
The MIR2052HG gene is a potential biomarker for various types of cancer, including breast, ovarian, and prostate cancer. The MIR2052HG gene is expressed in these cancer tissues and is associated with the poor prognosis of these diseases. The MIR2052HG gene has also been shown to be downregulated in various cancer cell lines, which suggests that it may be a promising target for cancer therapies.
The potential clinical applications of the MIR2052HG gene
The MIR2052HG gene has the potential to be a drug target for various diseases, including cancer. The MIR2052HG gene is involved in the regulation of miRNA expression, which is a crucial regulatory pathway in post-transcriptional gene regulation. Therefore, inhibiting the activity of the MIR2052HG gene may be a promising approach for treating various diseases, including cancer.
One of the potential clinical applications of the MIR2052HG gene is the treatment of cancer. The MIR2052HG gene is involved in the regulation of miRNA expression, which is a crucial regulatory pathway in post
Protein Name: MIR2052 Host Gene
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• general information;
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• expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
MIR2053 | MIR2054 | MIR205HG | MIR206 | MIR208A | MIR208B | MIR20A | MIR20B | MIR21 | MIR210 | MIR210HG | MIR211 | MIR2110 | MIR2113 | MIR2114 | MIR2115 | MIR2116 | MIR2117 | MIR212 | MIR214 | MIR215 | MIR216A | MIR216B | MIR217 | MIR217HG | MIR218-1 | MIR218-2 | MIR219A1 | MIR219A2 | MIR219B | MIR22 | MIR221 | MIR222 | MIR223 | MIR224 | MIR2276 | MIR2277 | MIR2278 | MIR22HG | MIR2355 | MIR2392 | MIR23A | MIR23AHG | MIR23B | MIR23C | MIR24-1 | MIR24-2 | MIR2467 | MIR25 | MIR2681 | MIR2682 | MIR26A1 | MIR26A2 | MIR26B | MIR27A | MIR27B | MIR28 | MIR2861 | MIR2909 | MIR296 | MIR297 | MIR298 | MIR299 | MIR29A | MIR29B1 | MIR29B2 | MIR29B2CHG | MIR29C | MIR300 | MIR301A | MIR301B | MIR302A | MIR302B | MIR302C | MIR302D | MIR302E | MIR302F | MIR3059 | MIR3064 | MIR3065 | MIR3074 | MIR3085 | MIR30A | MIR30B | MIR30C1 | MIR30C2 | MIR30D | MIR30E | MIR31 | MIR3115 | MIR3116-1 | MIR3116-2 | MIR3117 | MIR3118-1 | MIR3118-2 | MIR3118-3 | MIR3118-4 | MIR3118-5 | MIR3118-6 | MIR3119-1
