LSM8: A Protein with Potential Drug Targets and Biomarkers for Various Diseases

Target Name: LSM8

NCBI ID: G51691

LSM8

LSM8: A Protein with Potential Drug Targets and Biomarkers for Various Diseases

LSM8 (NAA38) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and muscle. It is a member of the LSM family of proteins, which are known for their role in intracellular signaling. LSM8 is also a key regulator of the Notch signaling pathway, which is involved in a wide range of physiological processes, including cell survival, growth, and differentiation.

In recent years, researchers have been interested in studying the potential drug targets of LSM8, as well as its potential as a biomarker for various diseases. One of the main reasons for this interest is the fact that LSM8 has been shown to play a role in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key features of LSM8 is its ability to interact with a variety of different signaling pathways. For example, LSM8 has been shown to interact with the Notch signaling pathway, as well as the TGF-β signaling pathway. This suggests that LSM8 may be involved in a wide range of physiological processes, including cell survival, growth, and differentiation.

In addition to its role in signaling pathways, LSM8 has also been shown to play a key role in the regulation of cellular processes that are important for overall cellular health. For example, LSM8 has been shown to be involved in the regulation of cell division, and in the regulation of cellular apoptosis, which is the process by which cells die when they are no longer needed.

Despite the potential clinical benefits of targeting LSM8, there are also concerns about the potential risks associated with these efforts. In particular, there is concern that any potential drug developed to target LSM8 could have unintended consequences, such as adverse side effects or an increased risk of disease.

Overall, LSM8 is a protein that has the potential to be a drug target or biomarker for a wide range of diseases. Further research is needed to fully understand its role in various biological processes and to develop safe and effective treatments.

Protein Name: LSM8 Homolog, U6 Small Nuclear RNA Associated

Functions: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320)

The "LSM8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LSM8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets