Ribosomal Protein L4: Key Protein Involved in Ribosome Function and Disease

Target Name: RPL4

NCBI ID: G6124

RPL4

Ribosomal Protein L4: Key Protein Involved in Ribosome Function and Disease

Ribosomal protein L4 (RPL4) is a protein that is synthesized in the ribosome, which is a protein complex that is responsible for synthesizing proteins in the cell. RPL4 is a key protein that is involved in the proper functioning of the ribosome, and it is often used as a drug target or biomarker in research.

RPL4 is a 28-kDa protein that is composed of 215 amino acids. It is located at the base of the third rRNA molecule in the ribosome and is responsible for the fidelity of the amino acid sequence in the rRNA molecule. RPL4 helps to ensure that the sequence of amino acids in the rRNA molecule is correct, which is essential for the production of correctly-sized and functionally-active proteins.

RPL4 functions by using a unique mechanism to check the sequence of amino acids in the rRNA molecule. It does this by using a small piece of RNA called the 23S rRNA, which contains a stretch of sequence-directed RNA that is complementary to the amino acid sequence in the protein. RPL4 is able to bind to this piece of RNA and use it to check the sequence of the amino acids in the rRNA molecule.

One of the unique features of RPL4 is its ability to interact with the 23S rRNA. This interaction allows RPL4 to detect changes in the sequence of the rRNA molecule that may indicate errors in the amino acid sequence. RPL4 is able to do this by using a specific sequence of amino acids in the 23S rRNA, which is known as the \"error-detection loop.\"

RPL4 is also involved in the regulation of protein synthesis in the cell. It does this by interacting with the rRNA molecule and the protein synthesis machinery. This interaction allows RPL4 to regulate the amount of protein that is synthesized in the cell, which can be useful for the study of diseases such as cancer and neurodegenerative disorders.

In addition to its role in protein synthesis, RPL4 is also involved in the regulation of gene expression. It does this by interacting with the RNA polymerase, which is the protein that reads the DNA code and synthesizes RNA from it. This interaction allows RPL4 to regulate the amount of RNA that is synthesized from the DNA, which can be useful for the study of gene function and the regulation of gene expression.

RPL4 is also involved in the regulation of DNA replication. It does this by interacting with the DNA replication machinery, which is responsible for copying the DNA code from one generation to the next. This interaction allows RPL4 to regulate the amount of DNA that is replicated in the cell, which can be useful for the study of cancer and other diseases.

In conclusion, RPL4 is a key protein that is involved in the proper functioning of the ribosome and the regulation of protein synthesis, gene expression, and DNA replication. Its unique ability to interact with the 23S rRNA makes it an attractive drug target and a potential biomarker for a variety of diseases. Further research is needed to fully understand the role of RPL4 in these processes and to develop effective treatments for the prevention and treatment of these diseases.

Protein Name: Ribosomal Protein L4

Functions: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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