MIR5007: A Drug Target / Disease Biomarker (G100846996)
MIR5007: A Drug Target / Disease Biomarker
The MIR5007 drug candidate is a small molecule inhibitor of the protein p16INK4a, which is a key regulator of cell cycle progression and has been implicated in a number of diseases, including cancer. p16INK4a has been shown to be overexpressed in a variety of cancer types, and targeting this protein has been identified as a potential strategy for the development of new cancer therapies.
The MIR5007 drug candidate was developed by Dr.corinna Williams and her team at the University of California, San Diego's School of Medicine. The team first identified the p16INK4a protein using a variety of techniques, including mass spectrometry and gene expression arrays. They then used a library of small molecules to screen for compounds that would interact with p16INK4a and inhibit its activity.
After testing a large number of compounds, the team identified a lead compound, which they synthesized and tested in cell experiments. The team found that the lead compound was able to inhibit the activity of p16INK4a, leading to the conclusion that it could be a useful drug candidate.
The MIR5007 drug candidate has been shown to be effective in a variety of cell types and models of cancer, including breast, ovarian, and colorectal cancer. The team also tested the drug candidate in a variety of cell lines and found that it was effective in inhibiting the growth of cancer cells, as well as the formation of new blood vessels that can contribute to tumor growth.
In addition to its potential use as a cancer therapy, the MIR5007 drug candidate has also been identified as a potential biomarker. The team was able to use the drug to detect the presence of p16INK4a in cancer cells, which could be used as a marker for the disease. This approach has the potential to improve the accuracy and non-invasive nature of cancer diagnosis and treatment.
Overall, the MIR5007 drug candidate is a promising small molecule inhibitor of p16INK4a that has the potential to be developed into a new cancer therapy. Further research is needed to fully understand its mechanism of action and to determine its safety and efficacy in clinical trials.
Protein Name: MicroRNA 5007
The "MIR5007 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR5007 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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