Target Name: BBOF1
NCBI ID: G80127
Review Report on BBOF1 Target / Biomarker Content of Review Report on BBOF1 Target / Biomarker
BBOF1
Other Name(s): Coiled-coil domain-containing protein 176 | basal body orientation factor 1 | C14orf45 | BBOF1_HUMAN | coiled-coil domain containing 176 | FBB10 | CCDC176 | Basal body-orientation factor 1 | Basal body orientation factor 1 | coiled-coil domain-containing protein 176

Unveiling the Potential of BBOF1: A Novel Drug Target and Biomarker

Protein domains are the building blocks of proteins and are known to play a crucial role in their structure, function, and regulation. Domain-containing proteins are a subclass of proteins that contain a specific domain and are involved in various cellular processes. BBOF1, or Coiled-coil domain-containing protein 176, is a protein that belongs to the BBOF1 family and has been identified as a potential drug target and biomarker.

In this article, we will provide an overview of BBOF1, its functions, potential drug targets, and potential use as a biomarker. We will discuss the research that has been done on BBOF1 and its potential implications for future drug development.

Overview of BBOF1

BBOF1 is a protein that contains a coiled-coil domain and is expressed in various tissues and organs, including brain, heart, liver, and kidney. It is a 22-kDa protein that consists of 118 amino acid residues. The protein has a characteristic coiled-coil structure, which is composed of two distinct regions: an N-terminal region and a C-terminal region.

The N-terminal region contains a unique domain that is composed of a helix and a loop. This domain is responsible for the protein's stability and functions as a binding site for other proteins. The C-terminal region contains a series of parallel beta-strands that form a distinct structural unit.

BBOF1 is involved in various cellular processes, including cell adhesion, migration, and signaling. It has been shown to play a role in the regulation of neurotransmitter release, neurogenesis, and stress response. BBOF1 has also been shown to be involved in the regulation of cell survival and has been linked to the development and progression of various diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases.

Potential Drug Targets

BBOF1 has several potential drug targets due to its unique structure and function. One of the most promising targets is the interaction between BBOF1 and neurotransmitters, such as dopamine and serotonin. BBOF1 has been shown to play a role in the regulation of neurotransmitter release and has been shown to interact with dopamine and serotonin receptors. Therefore, drugs that can modulate the activity of these receptors could be a good fit for BBOF1 as a drug target.

Another potential drug target for BBOF1 is its role in stress response. BBOF1 has been shown to be involved in the regulation of cellular stress responses and has been linked to the development of stress-induced neurodegeneration. Therefore, drugs that can modulate cellular stress responses could also be a good fit for BBOF1 as a drug target.

Potential Use as a Biomarker

BBOF1 has the potential to serve as a biomarker for various diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases. Its involvement in the regulation of cellular processes and its interaction with neurotransmitters and stress response make it an attractive candidate for use as a biomarker.

One of the most promising applications of BBOF1 as a biomarker is its potential to serve as a marker for neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. These disorders are characterized by the progressive loss of brain cells and are associated with the production of beta-amyloid plaques and neurodegenerate changes in the brain. BBOF1 has been shown to be involved in the regulation of beta-amyloid formation and has been linked to the development of beta-amyloid plaques. Therefore, BBOF1 has the potential

Protein Name: Basal Body Orientation Factor 1

Functions: Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues (By similarity)

The "BBOF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BBOF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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