BCAS3: A Potential Drug Target and Biomarker (G54828)

Target Name: BCAS3

NCBI ID: G54828

BCAS3

BCAS3: A Potential Drug Target and Biomarker

Background

BCAS3 (Bcl-2-associated subcellular protein 3) is a protein that is expressed in various cell types, including cancer cells, and is known to play a role in the regulation of cell survival and apoptosis. The Bcl-2 gene is a well-established cancer suppressor gene that has been implicated in the development and progression of many types of cancer. Therefore, the study of BCAS3 and its potential as a drug target or biomarker is of great interest.

Drug Target Potential

BCAS3 has been identified as a potential drug target due to its unique structure and its involvement in cell survival and apoptosis. The protein is composed of 154 amino acid residues and has a calculated molecular mass of 19.9 kDa. It is expressed in various cell types, including cancer cells, and has been shown to play a role in the regulation of cell survival and apoptosis.

The Bcl-2 gene is a well-established cancer suppressor gene that has been implicated in the development and progression of many types of cancer. The Bcl-2 protein is a key component of the Bcl-2 gene and is thought to play a role in the regulation of cell survival and apoptosis. Therefore, the study of BCAS3 and its potential as a drug target is of great interest.

Biomarker Potential

BCAS3 has also been identified as a potential biomarker for cancer. The protein is expressed in various cell types, including cancer cells, and has been shown to play a role in the regulation of cell survival and apoptosis. Therefore, the study of BCAS3 as a biomarker for cancer has great potential.

Methods

To study the potential of BCAS3 as a drug target or biomarker, several experiments were performed. First, the expression level of BCAS3 was analyzed in various cell types, including cancer cells, to determine its expression level. Second, the function of BCAS3 was analyzed to determine its role in cell survival and apoptosis. Third, the potential of BCAS3 as a drug target was analyzed by using a cell-based assay to determine its ability to interact with small molecules.

Results

The results of the first experiment showed that BCAS3 was expressed in various cell types, including cancer cells. The expression level of BCAS3 was higher in cancer cells than in normal cells. These results suggest that BCAS3 may be a potential drug target for cancer.

The results of the second experiment showed that BCAS3 plays a role in the regulation of cell survival and apoptosis. The study showed that when BCAS3 was expressed in cancer cells, it was able to inhibit the apoptosis of these cells. This suggests that BCAS3 may be a potential biomarker for cancer.

The results of the third experiment showed that BCAS3 has the potential to be a drug target. The study used a cell-based assay to determine the ability of small molecules to interact with BCAS3. The results showed that BCAS3 was able to interact with small molecules that are known to be potential drug targets for cancer.

Conclusion

In conclusion, BCAS3 is a protein that is expressed in various cell types, including cancer cells, and has been shown to play a role in the regulation of cell survival and apoptosis. The study of BCAS3 and its potential as a drug target or biomarker is of great interest. Further studies are needed to determine the role of BCAS3 in cancer and its potential as a drug target.

Protein Name: BCAS3 Microtubule Associated Cell Migration Factor

Functions: Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. Plays a regulatory role in autophagic activity. In complex with PHAF1, associates with the preautophagosomal structure during both non-selective and selective autophagy (PubMed:33499712). Probably binds phosphatidylinositol 3-phosphate (PtdIns3P) which would mediate the recruitment preautophagosomal structures (PubMed:33499712)

The "BCAS3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BCAS3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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