ZSWIM1: A Potential Drug Target and Biomarker (G90204)

Target Name: ZSWIM1

NCBI ID: G90204

ZSWIM1

ZSWIM1: A Potential Drug Target and Biomarker

Introduction

Zinc finger genes (ZFGs) are a family of non-coding RNAs that play a crucial role in various cellular processes, including gene regulation, DNA replication, and repair, DNA binding, and signaling pathways. ZSWIM1, a zinc finger gene located in the SWIM domain, has been identified as a potential drug target and biomarker. This article will explore the biology of ZSWIM1, its potential drug target status, and its potential as a biomarker for various diseases.

biological background

Zinc finger genes (ZFGs) are a class of noncoding RNAs that play important roles in various cellular processes, including gene regulation, DNA replication, repair, DNA binding, and signaling pathways. ZSWIM1, a zinc finger gene located in the SWIM domain, has been identified as a potential drug target and biomarker. This article will explore the biology of ZSWIM1, its status as a potential drug target, and its potential as a biomarker for various diseases.

Functions of ZSWIM1

ZSWIM1 forms a gene expression element in the nucleus, including a SWIM domain, an N-terminal and a C-terminal domain. The SWIM domain is a secondary structural domain composed of nine conserved zinc finger sequences, including an 伪-helix, a 尾-sheet, and two antiparallel 尾-伪 helices. The N-terminal and C-terminal domains contain multiple noncoding RNA binding sites (NBPs) and binding elements (BEs), and these domains are involved in the regulation of gene expression.

The biological function of ZSWIM1 has been confirmed in multiple studies. ZSWIM1 plays a role in maintaining the stability of gene expression, regulating cell cycle, participating in DNA replication and repair, regulating apoptosis, anti-inflammatory and immune responses. Variations in ZSWIM1 are closely related to the occurrence and development of various diseases, such as cancer, neurodegenerative diseases, immune deficiencies and autoimmune diseases.

potential drug targets

The status of ZSWIM1 as a potential drug target was obtained through multiple experimental evidences. First, ZSWIM1 is up-regulated in a variety of cancer cells, and the expression level is positively correlated with disease severity. Secondly, ZSWIM1 is closely related to the survival and proliferation of various cancer cells, and its expression level is positively correlated with disease progression and treatment response. In addition, ZSWIM1 is also closely related to the onset and development of neurodegenerative diseases, immune deficiencies, autoimmune diseases and other diseases.

potential biomarkers

The potential biomarker properties of ZSWIM1 have been confirmed in multiple studies. ZSWIM1 can be used as a biomarker for diseases such as tumors and neurodegenerative diseases with high sensitivity and specificity. In addition, ZSWIM1 can also be used as an indicator for monitoring the efficacy of therapeutic drugs because its expression level is positively correlated with the therapeutic effect.

in conclusion

ZSWIM1, as a zinc finger gene, plays an important role in cell biology and disease occurrence. In-depth research on its functions provides a theoretical basis for finding new drug targets and biomarkers. With further research on ZSWIM1 as a drug target and biomarker, it is expected to bring new hope for the treatment of various diseases.

Protein Name: Zinc Finger SWIM-type Containing 1

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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