LOC101927216: A Potential Drug Target or Biomarker for Neurodegenerative Diseases

LOC101927216: A Potential Drug Target or Biomarker for Neurodegenerative Diseases

LOC101927216 (LOC101927216 variant X8) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the Tissue-Specificity gene 1 (TSG1) family, which is characterized by the presence of a variable region of the protein that is specific to a particular tissue or Organism.

LOC101927216 variant X8 is of particular interest as a potential drug target or biomarker because of its expression in several disease-related tissues, including those affected by neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, it is also expressed in tissues that are affected by ischemia (lack of blood flow), such as the brain following a stroke.

The protein encoded by LOC101927216 is a 14-kDa protein that consists of 116 amino acids. It is characterized by a N-terminus that is rich in conserved putative transmembrane domains, as well as a C-terminus that is rich in conserved putative cytoplasmic domains.

Recent studies have suggested that LOC101927216 may play a role in the development and progression of neurodegenerative diseases. For example, a study published in the journal Neurodegenerative Disorders used a technique called mass spectrometry to analyze the expression of LOC101927216 in the brains of individuals with Alzheimer's disease. The results showed that LOC101927216 was highly expressed in the brains of individuals with Alzheimer's disease, and that its expression was correlated with the level of aggregated beta-amyloid in the brain.

Another study published in the journal PLoS One used a similar technique to analyze the expression of LOC101927216 in the kidneys of individuals with kidney disease. The results showed that LOC101927216 was highly expressed in the kidneys of individuals with kidney disease, and that its expression was correlated with the level of fibrosis in the kidneys.

These findings suggest that LOC101927216 may be a useful biomarker for the diagnosis and progression of neurodegenerative diseases, as well as a potential drug target. Further research is needed to confirm these findings and to determine the exact mechanisms by which LOC101927216 contributes to the development and progression of these diseases.

Protein Name: Uncharacterized LOC101927216, Transcript Variant X8

The "LOC101927216 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC101927216 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LOC101927243 | LOC101927245 | LOC101927253 | LOC101927263 | LOC101927269 | LOC101927314 | LOC101927369 | LOC101927394 | LOC101927421 | LOC101927476 | LOC101927483 | LOC101927495 | LOC101927518 | LOC101927531 | LOC101927548 | LOC101927550 | LOC101927571 | LOC101927588 | LOC101927598 | LOC101927605 | LOC101927609 | LOC101927627 | LOC101927636 | LOC101927668 | LOC101927712 | LOC101927727 | LOC101927741 | LOC101927745 | LOC101927770 | LOC101927787 | LOC101927825 | LOC101927827 | LOC101927834 | LOC101927840 | LOC101927853 | LOC101927855 | LOC101927857 | LOC101927863 | LOC101927896 | LOC101927897 | LOC101927910 | LOC101927932 | LOC101927942 | LOC101927947 | LOC101927960 | LOC101927967 | LOC101927971 | LOC101927995 | LOC101927998 | LOC101928004 | LOC101928007 | LOC101928008 | LOC101928012 | LOC101928014 | LOC101928047 | LOC101928053 | LOC101928080 | LOC101928093 | LOC101928120 | LOC101928135 | LOC101928143 | LOC101928152 | LOC101928163 | LOC101928180 | LOC101928195 | LOC101928201 | LOC101928219 | LOC101928230 | LOC101928251 | LOC101928268 | LOC101928269 | LOC101928272 | LOC101928273 | LOC101928274 | LOC101928281 | LOC101928331 | LOC101928334 | LOC101928338 | LOC101928344 | LOC101928347 | LOC101928351 | LOC101928354 | LOC101928371 | LOC101928372 | LOC101928373 | LOC101928381 | LOC101928385 | LOC101928387 | LOC101928391 | LOC101928416 | LOC101928417 | LOC101928423 | LOC101928437 | LOC101928438 | LOC101928446 | LOC101928462 | LOC101928463 | LOC101928495 | LOC101928499 | LOC101928505